英文名稱：
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE
CAS號(hào)：
80288-49-9
分子式：
C12H12N4O3
分子量：
260.25
EINECS號(hào)：
200-158-5
沸點(diǎn)
543.6±60.0 °C(Predicted)
密度
1.443±0.06 g/cm3(Predicted)
溶解度
ethanol: 0.33 mg/mL
酸度系數(shù)(pKa)
8.62±0.70(Predicted)
形態(tài)
solid
顏色
white
InChIKey
KGQZGCIVHYLPBH-UHFFFAOYSA-N
Furafylline is a selective inhibitor of cytochrome P450IA2 (IC50 = 2.4 μM) and PDE (phosphodiesterase). Furafylline is a methyl xanthine derivative with an expanded duration of action in vivo than that of theophylline. Inhibition of CYP has the effect of slowing oxidative metabolism of xenobiotics, while inhibition of PDE prevents the hydrolysis of secondary messenger molecules, which in turn prolongs signal transduction and enhances its effects.
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