中文名稱

8- [4-（1-氨基環(huán)丁基）苯基] -9-苯基-1,2,4-三唑并[3,4-f] [1,6]萘啶-3（2H）-二鹽酸鹽

英文名字

8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, dihydrochloride

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開曼生物

產(chǎn)品貨號

11593-5

產(chǎn)品報價

￥1/5mg

產(chǎn)品說明書

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產(chǎn)品新聞

背景資料

Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKB

產(chǎn)品描述

An orally active, allosteric Akt inhibitor (IC50s = 5, 12, and 65 nM for Akt1, 2, and 3, respectively); inhibits cell proliferation of human cancer cell lines synergistically in combination with other topoisomerase inhibitors, antimetabolites, antimicrotubule agents, DNA cross-linkers or growth factor inhibitors

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