中文名稱

17β-雌二醇17-（β-D-葡糖醛酸）|17β-雌二醇17-（β-D-葡糖醛酸）| E217G |β-雌二醇17-（β-D-葡糖醛酸）；（17β）-3-羥基estra-1,3,5（10）-三烯-17-基β-D-吡喃葡萄糖苷神經醛酸，單鈉鹽

英文名字

17β-Estradiol 17-(β-D-glucuronide)|17β-Oestradiol 17-(β-D-glucuronide)|E217G|β-Estradiol 17-(β-D-glucuronide); (17β)-3-hydroxyestra-1,3,5(10)-trien-17-yl β-D-glucopyranosiduronic acid, monosodium salt

供應商

開曼生物

產品貨號

16156-50

產品報價

￥5266.8/50mg

產品說明書

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購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料

Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.{26342} It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km = 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.{26342,26341} In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transport via MRP2 and the transport of other MRP2 substrates, including the non-cholestatic estrogen metabolite, estradiol 3-(β-D-glucuronide) (E23G; Item No. 16155).{26341,26340} E217G has also been reported to be transported by MDR1, MRP1, MRP3, MRP4, MRP7, ABCG2 (a breast cancer resistance protein transporter), and the rat organic anion-transporting polypeptides 1-4.{26341}

產品描述

An estrogen metabolite that acts as a substrate of MRP2 (Km = 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow

保存建議

建議您在收到開曼生物品牌的Estradiol 17-(β-D-glucuronide) (sodium salt) (50 mg)產品后置于-20度保存，產品有效期為730天.

其他

開曼生物向全球科學工作者提供多研究領域的生化、免疫試劑和分析試劑盒，其產品被廣泛應用于腫瘤、氧化氮、神經學、凋亡、氧化性損傷、內分泌學等不同研究領域.開曼生物可提供用于檢測的特色試劑盒，如：類花生酸類物質、游離的生物標志、環(huán)核苷、激素及氧化氮等；也提供多種高質量試劑，包括：類花生酸類物質、氧化氮試劑及許多相關脂質、脂肪酸、酶和抗體.作為開曼生物在中國的區(qū)域總代理，艾美捷科技有限公司將為中國客戶提供最全面的開曼生物產品以及客戶訂制化服務.