Description: Acifran is a hypolipidaemic agent more potent than nicotinic acid and clofibrate. Acifran is an agonist of human orphan GPCR HM74A/GPR109A and HM74B (GPR109B) and has been shown to reduce serum triglycerides and circulating LDL-cholesterol in vivo, without having an effect on liver weight or liver enzymes.
Name: Acifran
CAS#: 72420-38-3
Chemical Formula: C12H10O4
Exact Mass: 218.0579
Molecular Weight: 218.21
Elemental Analysis: C, 66.05; H, 4.62; O, 29.33
IUPAC/Chemical Name: 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
InChi Key: DFDGRKNOFOJBAJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)
SMILES Code: O=C(C(OC1(C)C2=CC=CC=C2)=CC1=O)O
Appearance: Solid powder
關(guān)鍵字： 72420-38-3;
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