Rabbit Anti-5HT2A Receptor Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:5HT2A Receptor
IR:Immunogen Range:171-270/471
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3356
Swiss Prot:P28223
Source:KLH conjugated synthetic peptide derived from human 5HT2A Receptor:171-270/471
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:5HT2A receptor is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. 5HT2A receptor belongs to the G-protein coupled receptor 1 family and mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. 5HT2A receptor is an integral membrane protein which localizes to the post-synaptic thickening of axo-dendritic synapses. 5HT2A receptor protein contains a PDZ domain-binding motif which is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： 5HT2A Receptor;HTR2A;5-hydroxytryptamine ;HTR2;5-HT-2;5-HT-2A;Serotonin receptor 2;5HT2A_HUMAN;
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