Rabbit Anti-eIF4EBP1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:eIF4EBP1
IR:Immunogen Range:65-118/118
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1978
Swiss Prot:Q13541
Source:KLH conjugated synthetic peptide derived from human 4E-BP1:65-118/118
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Goat
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： eIF4EBP1;Eukaryotic translati;4E-BP1;eIF4E-binding protei;Phosphorylated ;heat- and acid-stabl;insulin 1 (PHAS-I);4EBP1_HUMAN;
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