Rabbit Anti-AANAT Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:AANAT
IR:Immunogen Range:141-207/207
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:15
Swiss Prot:Q16613
Source:KLH conjugated synthetic peptide derived from human AANAT:141-207/207
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： AANAT;AANAT;Arylalkylamine ;N acetyltransferase;Serotonin ;acetyltransferase;SNAT;SNAT_HUMAN;
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