Rabbit Anti-IRF4 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:IRF4
IR:Immunogen Range:301-400/451
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3662
Swiss Prot:Q15306
Source:KLH conjugated synthetic peptide derived from human IRF-4:301-400/451
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Cow
Horse
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： IRF4;Interferon regulator;IRF4;LSIRF;NFEM5;OTTHUMP00000017905;PU.1 interaction par;IRF4_HUMAN;
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