Rabbit Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-BLNK (Tyr96)
IR:Immunogen Range:DS(p-Y)EP
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:29760
Swiss Prot:Q8WV28
Source:KLH conjugated Synthesised phosphopeptide derived from human BLNK around the phosphorylation site of Tyr96:DS(p-Y)EP
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Cross Reactive Species:Human
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僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： Phospho-BLNK (Tyr96);BLNK (phospho Y96); p-BLNK (phospho Y96; B cell adapter cont;BASH;Bca;Lyw57;MGC111051;
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