Rabbit Anti-CDC10 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CDC10
IR:Immunogen Range:201-300/437
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:989
Swiss Prot:Q16181
Source:KLH conjugated synthetic peptide derived from human Septin 7:201-300/437
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Cow
Zebrafish
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： CDC10;Cdc3p;SEPT7A;CDC10;CDC10 protein homolo;CDC3; Cell division cycle;SEPT7_HUMAN;
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