Rabbit Anti-phospho-TIRAP (Tyr86) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-TIRAP (Tyr86)
IR:Immunogen Range:KD(p-Y)DV
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:114609
Swiss Prot:P58753
Source:KLH conjugated Synthesised phosphopeptide derived from human TIRAP around the acetylation site of Tyr86:KD(p-Y)DV
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The Toll-like receptor (TLR) family in mammals comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TIRAP (TIR domain-containing adaptor protein) is an adaptor protein used by TLR4. Blocking TIRAP inhibits TLR4-mediated signaling events, including DC maturation and cytokine production.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Dog
Pig
Cow
Horse
Guinea Pig
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： phospho-TIRAP (Tyr86;TIRAP (phospho Y86);Adapter protein wyat;MAL antibody MyD88 a;TIR domain containin;Toll interleukin 1 r;Toll like receptor a;Wyatt;
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