Rabbit Anti-phospho-Brk (Tyr447) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-Brk (Tyr447)
IR:Immunogen Range:TS(p-Y)EN
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5753
Swiss Prot:Q13882
Source:KLH conjugated synthesised phosphopeptide derived from human Brk around the phosphorylation site of Tyr447:TS(p-Y)EN
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This protein encoded is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphorylation.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(3μg/Test)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： phospho-Brk (Tyr447);Brk (phospho Y447);p-Brk (phospho Y447);Breast tumor kinase;Breast tumour kinase;PTK6;Tyrosine protein kin;PTK6_HUMAN;
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