| 中文名稱:CWHM-12 | 英文名稱:CWHM-12 |
| CAS:1564286-55-0 | 純度規(guī)格: 99% |
| 產(chǎn)品類別: 生物試劑 |
CWHM-12是αV整聯(lián)蛋白的有效抑制劑,抑制αvβ8,αvβ3,αvβ6和αvβ1的 IC50 值分別為0.2,0.8,1.5,1.8 nM。Mice are treated with CCl4 for 3 weeks to establish fibrotic disease and then treated with CWHM-12 (CWHM 12) or vehicle for the final 3 weeks of CCl4. CWHM-12 significantly reduces liver fibrosis even after fibrotic disease have been established. Digital image quantitation demonstrates significantly reduced p-SMAD3 signaling in the livers of CWHM-12 treated mice compare to controls, demonstrating that the protection from CCl4-induced hepatic fibrosis observed in CWHM-12 treated mice is due at least in part to a reduction in TGF-β activation by αv integrins. Besides, administration of CWHM-12 significantly inhibited progression of pulmonary fibrosis
| 成立日期 | 2021-03-31 (6年) | 注冊(cè)資本 | 20萬(wàn)人民幣 |
| 員工人數(shù) | 1-10人 | 年?duì)I業(yè)額 | ¥ 100萬(wàn)以內(nèi) |
| 主營(yíng)行業(yè) | 醫(yī)藥中間體,原料藥,有機(jī)合成藥,氨基酸及其衍生物 | 經(jīng)營(yíng)模式 | 工廠,試劑,定制 |
| 產(chǎn)品名稱 | 價(jià)格 | 公司名稱 | 報(bào)價(jià)日期 | |
|---|---|---|---|---|
| 詢價(jià) |
VIP7年
|
上海澤葉生物科技有限公司
|
2026-07-29 | |
| 詢價(jià) |
VIP5年
|
TargetMol中國(guó)(陶術(shù)生物)
|
2026-06-29 | |
| ¥899.90 |
VIP3年
|
上海阿拉丁生化科技股份有限公司
|
2026-06-10 |