中文名：2-溴-4′-甲氧基苯乙酮

英文名：2-Bromo-4′-methoxyacetophenone

應(yīng)用：A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor.

純度：≥98%

貨號(hào)：B101897

Cas號(hào)：2632-13-5

存儲(chǔ)溫度：2-8°C儲(chǔ)存

運(yùn)輸條件：低溫運(yùn)輸

產(chǎn)品介紹：

PTP inhibitor II is a cell-permeable, covalent and potent PTP (protein tyrosine phosphatase) inhibitor. The compound acts by binding the catalytic domain of the SH2 domain-containing phosphatase SHP-1(DSH2). PTP inhibitor II binds with lower affinity than PTP Inhibitor I (Ki = 128 μM and Ki = 43 μM respectively). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm. PTP inhibitors have demonstrated enhanced clonogenic survival, mutagenesis and cell growth. PTP inhibitors can also be useful for probing signal transduction pathways as well as drμgs for treatment of PTP-related diseases. PTP Inhibitor II is an inhibitor of PTP1B and SH-PTP1.A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor.

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