中文名：7,8-二羥基黃酮水合物

英文名：7,8-Dihydroxyflavone Hydrate

純度：≥98%(HPLC)

貨號：D137213

Cas號：38183-03-8

存儲溫度：2-8°C儲存,充氬

運輸條件：低溫運輸

產(chǎn)品介紹：

7,8-Dihydroxyflavone hydrate is a tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor with a Kd value of 320 nM. It also inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro.7,8-Dihydroxyflavone (7,8-DHF), a selective tyrosine kinase receptor B (neurotrophic factor/tropomyosin-receptor-kinase B; TrkB) agonist, may be used to help identify and differentiate the physiological effects and cell signaling pathways mediated by TrkB activation, such as those involving neuroprotection, memory, vasorelaxation and hypertension. 7,8-Dihydroxyflavone may be used to study its effects on scopolamine induced Alzheimer-like pathologic dysfunction.

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