中文名：歐前胡素

英文名：Imperatorin

應(yīng)用：

純度：≥98%(HPLC)

貨號(hào)：I114064

Cas號(hào)：482-44-0

存儲(chǔ)溫度：-20°C儲(chǔ)存

運(yùn)輸條件：超低溫運(yùn)輸

產(chǎn)品介紹：

屬呋喃香豆素類化合物。為棱柱狀結(jié)晶（由乙醚）、長(zhǎng)細(xì)針晶（由熱水），易溶于氯仿，可溶于苯、乙醇、乙醚和苛性堿溶液，不溶于冷水。 Imperatorin is a furocoumarin present in citrus fruits, which is used in HIV-1 research. Studies indicate that the transcription factor Sp1 is essential in the inhibitory functions of Imperatorin. In addition, Imperatorin inhibits cyclin D1 expression and stops the cell cycle at G1. These studies also sμggest that Imperatorin suppresses HIV-1 replication in primary T lymphocytes and transformed cell lines. Furthermore, it has been sμggested that the inhibitory effects of Imperatorin on HIV-1 at the transcriptional level can be monitored effectively in HeLa cells. Imperatorin can also cause apoptosis in human promyelocytic leukaemia, HL-60 via the cytochrome c/caspase-9 pathway.

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