白色或類白色結(jié)晶性粉末，幾無(wú)臭，味苦。易溶于甲醇或稀鹽酸，溶于乙醇，略溶于異丙醇，微溶于水。熔點(diǎn)141～143℃。37℃時(shí)在水中的溶解度為1.14%。急性毒性LD₅₀小鼠，大鼠(mg/kg)：2600，5000口服；150，106靜脈注射；470，650腹腔注射。組胺H2受體拮抗劑。能抑制組胺刺激引起的胃酸分泌，又能抑制由食物、五肽胃泌素、咖啡因和胰島素等所誘發(fā)的胃酸分泌，還能抑制基礎(chǔ)胃酸分泌。用于胃及十二指腸潰瘍、消化性食道炎、卓-艾綜合癥。用于治療消化性潰瘍。

White Solid.Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output.antibacterial.White crystals with a slight sulfur-mercaptan odor.Slightly water soluble.Flash point data for Cimetidine are not available. Cimetidine is probably combustible.Widely used H 2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I 1 imidazoline binding site ligand.