中文名：6,7-二甲氧基香豆素

英文名：6,7-Dimethoxycoumarin

純度：≥98%

貨號：D101246

Cas號：120-08-1

存儲溫度：室溫

運輸條件：常規(guī)運輸

產品介紹：

Scoparone is a compound found in the herb, Yin Chin, that can up-regulate the expression and activate the CAR (constitutive androstane receptor) found in the liver. It has been shown to clear the accumulation of bilirubin by the activation of CAR in neonatal jaundice. Other studies show that scaparone inhibits lipopolysaccharide (LPS)-induced tissue factor (TF) expression in HUVECs and that it acts as an anti-inflammatory compound. TCPOBOP also transactivates CAR, however, scoparone can activate murine and human CAR. Scaparone can increase dopamine release by synapsin I phosphorylation throμgh activation of PKA and CaMKII? in PC12 cells. It can also activate neurite outgrowth and improve dopamine biosynthesis in PC12 cells.An agent that can up-regulate the expression and activate CAR

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