分子名稱：FGL2

英文名稱：Fibronectin-2
中文名稱：纖維連接素-2

分子別稱：FGL2,Fibroleukin,Pt49

表達區(qū)間及表達系統(tǒng)（Source）

Human FGL2 (204-439) Protein, His Tag (FG2-H5243) is expressed from human 293 cells (HEK293). It contains AA Pro 204 - Pro 439

蛋白結(jié)構(gòu)（Molecular Characterization）

This protein carries a polyhistidine tag at the N-terminus

The protein has a calculated MW of 29.6 kDa. The protein migrates as 36-41 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>90% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;

2. -70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

Fibronectin-2，也稱為FGL2，是一種在體內(nèi)表現(xiàn)出多效性作用的蛋白質(zhì)，是先天和適應(yīng)性反應(yīng)的重要免疫調(diào)節(jié)因子。該蛋白以II型跨膜蛋白的形式存在于巨噬細(xì)胞和內(nèi)皮細(xì)胞表面（其羧基末端位于質(zhì)膜的細(xì)胞外側(cè)），并且可由CD4+和CD8+T細(xì)胞組成性分泌。