BDNF產(chǎn)品信息
英文名稱：Brain-derived neurotrophic factor
中文名稱：腦源性神經(jīng)營養(yǎng)因子
靶點別稱：BDNF,ANON2,BULN2,Abrineurin
物種：Human
標(biāo)簽：Tag Free
屬性：Protein
標(biāo)記：Unconjugated
蛋白結(jié)構(gòu)（Molecular Characterization）
This protein carries no "tag"
The protein has a calculated MW of 13.5 kDa. The protein migrates as 15-17 kDa and 19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素（Endotoxin）
Less than 0.01 EU per μg by the LAL method.
無菌（Sterility）
The sterility testing was performed by membrane filtration method.
支原體（Mycoplasma）
Negative.
純度（Purity）
>95% as determined by SDS-PAGE.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
BDNF分子背景
Brain-derived neurotrophic factor (BDNF) along with nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) are members of the neurotrophin family of trophic factors. The neurotrophins play essential roles in the development, survival, and function of a wide range of neurons in both the peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser extent).
關(guān)鍵字： BDNF;BDNF蛋白;腦源性神經(jīng)營養(yǎng)因子;ANON2;ANON2蛋白;
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