IFN-alpha/beta R1產(chǎn)品信息

英文名稱(chēng)：Interferon-alpha/beta receptor alpha chain

中文名稱(chēng)：干擾素α/β受體α鏈

靶點(diǎn)別稱(chēng)：IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1

物種：Human/Mouse/Cynomolgus

屬性：Protein

標(biāo)記：Protein-coupled magnetic beads/Biotin-labeled/Unconjugated

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>90% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲(chǔ)（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

IFN-alpha/beta R1分子背景

干擾素α/β受體1（IFNAR1）也稱(chēng)為細(xì)胞因子受體II類(lèi)成員1、細(xì)胞因子受體家族2成員1（CRF2-1）、I型干擾素受體1、IFNAR，屬于II型細(xì)胞因子受體族。IFNAR1/IFNAR包含四個(gè)纖維連接蛋白III型結(jié)構(gòu)域。IFNAR1與IFNAR2結(jié)合形成I型干擾素受體。IFNAR1是干擾素α和β的受體。IFNAR1可以在沒(méi)有IFNAR2的幫助下轉(zhuǎn)導(dǎo)IFNB信號(hào)，并且不會(huì)激活Jak-STAT通路。