Integrin alpha 4 beta 1產(chǎn)品信息

英文名稱：Integrin alpha-4/beta-1

中文名稱：整合素α-4/β-1復(fù)合體

靶點(diǎn)別稱：Integrin alpha4beta1

物種：Human

屬性：Protein

標(biāo)記：Biotin-labeled/Unconjugated

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>90% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

Integrin alpha 4 beta 1分子背景

整合素是跨膜蛋白，介導(dǎo)相鄰細(xì)胞和/或細(xì)胞外基質(zhì)（ECM）上的粘附分子之間的相互作用。整合素在幾個(gè)生物過程中具有不同的作用，包括發(fā)育和傷口愈合過程中的細(xì)胞遷移、細(xì)胞分化和凋亡。它們的活性還可以調(diào)節(jié)腫瘤細(xì)胞的轉(zhuǎn)移和侵襲潛力。整合素α4β1（alpha-4/β-1）是纖維連接蛋白的受體。整合素α-4/β-1是VCAM-1的受體，識別VCAM-1中的序列Q-I-D-S。