Integrin α8β1產(chǎn)品信息

別稱：Integrin alpha 8 beta 1,Integrin α8β1

物種：Human/Rat

屬性：Protein

標(biāo)記：Biotin-labeled/Unconjugated

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>95% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

Integrin α8β1分子背景

重組人整合素α8β1異二聚體蛋白由ITGA8和ITGB1組成。通過低嚴(yán)格雜交分離的整合素α8亞基是一種與β1相關(guān)的新型整合素亞基。最近發(fā)現(xiàn)的α8整合素亞基與β1結(jié)合，主要在成人組織的平滑肌和其他收縮細(xì)胞中表達(dá)，并在發(fā)育過程中在間充質(zhì)細(xì)胞和神經(jīng)細(xì)胞中表達(dá)。此外，整合素α8β1是纖維連接蛋白的受體，可以促進(jìn)纖維連接蛋白上的附著、細(xì)胞擴(kuò)散和神經(jīng)突起生長。