中文名：他扎羅汀酸
英文名：Tazarotenic acid
純度：≥98%(HPLC)
貨號：T302268
Cas號：118292-41-4
存儲溫度：2-8°C儲存
運(yùn)輸條件：低溫運(yùn)輸
產(chǎn)品介紹：
white to light brown powder
Biochemical/Physiological Effects：
Tazarotene is transformed to tazarotenic acid with the help of esterases. Tazarotenic acid regulates the pathogenic aspects of psoriasis through normalizing abnormal keratinocyte differentiation. It possesses strong anti-hyperproliferative effects in skin and reduces inflammation.
Tazarotenic acid, an active metabolite of tazarotene, is a potent and selective agonist of the retinoid receptor (RAR) that binds to RARα, RARβ, and RARγ. Tazarotenic acid relatively selective activates RARβ and RARγ. Tazarotenic acid is a first xenobiotic substrate of human retinoic acid hydroxylase CYP26A1 and CYP26B1.
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關(guān)鍵字： DDBEP ; 6-[2-(4,4-dimethyl-2,3-dihydro-1-benzothiopyran-6-yl)ethynyl]-3-pyridinecarboxylic acid ; 6-((4,4-Dimethylthiochroman-6-yl)ethynyl)nicotinic acid ; 6-[(4,4-dimethyl-3,4-dihydro-2H-1-benzothiopyran-6-yl)ethynyl]nicotinic acid
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