Human latent GDF-8 Protein, His Tag (MALS verified)
分子別名（Synonym）
latent GDF-8, GDF-8, Myostatin, GDF8, MSTN, Growth,differentiation factor 8
表達區(qū)間及表達系統（Source）
Human latent GDF-8, His Tag (GD8-H5243) is expressed from human 293 cells (HEK293). It contains AA Asn 24 - Ser 375 (Accession # O14793-1).
Predicted N-terminus: His
蛋白結構（Molecular Characterization）
This protein carries a polyhistidine tag at the N-terminus. The protein migrates as 14kDa, 35 kDa and 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE), speculated as mature GDF-8, propeptide and latent GDF-8 respectively due to glycosylation.
內毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
純度（Purity）
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4,0.2M Arg with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景（Background）
生長分化因子8（GDF8），也稱為肌肉生長抑制素，是在人顆粒細胞中表達的轉化生長因子-β超家族的獨特成員，在調節(jié)多種卵巢功能中具有重要作用。GDF8充當骨骼肌生長和分化的負調節(jié)劑。除了在肌肉骨骼系統中的表達外，GDF8還在包括生殖系統在內的各種組織中表達。
關鍵字： GDF-8;GDF-8蛋白;GDF-8重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group（股票代碼：301080）是成立于2010年的跨國生物科技公司，是為全球生物醫(yī)藥、健康產業(yè)領域提供關鍵生物試劑產品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球，橫跨亞洲、北美洲、歐洲，在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產基地。目前累計服務客戶超6000家，與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下擁有品牌ACROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。