化合物 D-Lin-MC3-DMA|T5823

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價(jià)格	詢價(jià)
包裝	1removed

最小起訂量	1removed
發(fā)貨地	上海
更新日期	2026-05-08

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產(chǎn)品詳情

中文名稱:化合物 D-Lin-MC3-DMA	英文名稱:D-Lin-MC3-DMA
CAS:1224606-06-7	品牌: TargetMol
產(chǎn)地: 美國	保存條件: Keep away from moisture,Store at low temperature,Keep away from direct sunlight Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
純度規(guī)格: 99.69%	產(chǎn)品類別: 抑制劑
貨號: T018\|T5823

Product Introduction

Bioactivity

名稱	D-Lin-MC3-DMA
描述	D-Lin-MC3-DMA is a siRNA delivery vector, an ionizable amino-lipid compound. D-Lin-MC3-DMA offers advantages of high loading efficiency, low toxicity, and efficient endosomal escape.
細(xì)胞實(shí)驗(yàn)	White leghorn chicken embryos at stage 24 (30) were removed and dissected in Hanks buffered saline solution (HBSS).?Forelimbs were pooled and treated for 1 h in dispase to remove epithelial ectoderm.?Limb mesenchyme was dissociated, and resuspended in DMEM with 5% FBS and 1% penicillin/streptomycin.?Cells were plated onto 96-well plates at a density of 2x10^5 or 2x10^7 cells/ml and treated with 0-40 μg/ml LNP-pDNA.?Cultures were incubated overnight at 37℃ and resuspended in PBS buffer for expression analysis using a BD LSRII flow cytometer.?Cell survival was assessed in low-density cultures after 24 h of treatment, by counting the adherent cells remaining after PBS washes.?Viability was determined based on average counts of all adherent cells within a single field of view (100x) normalized to cell counts of untreated cultures.
體外活性	將DSPC替換為不飽和PCs，并將DLin-MC3-DMA替換為相關(guān)脂質(zhì)DLin-KC2-DMA，可顯著提高HeLa細(xì)胞體外轉(zhuǎn)染試劑的效能。
存儲條件	Keep away from moisture,Store at low temperature,Keep away from direct sunlight Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
溶解度	Ethanol : 16.67 mg/mL (25.96 mM), Sonication and heating are recommended. DMSO : 43.33 mg/mL (67.48 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2.00 mg/mL (3.11 mM), Sonication is recommended.
關(guān)鍵字	Inhibitor \| inhibit \| D-Lin-MC3-DMA \| D-Lin-MC-3-DMA \| DLinMC3DMA \| D Lin MC3 DMA
相關(guān)產(chǎn)品	Cholesterol \| Benzyl nicotinate \| DOPE \| DSPS \| 1,2-Distearoyl-sn-glycero-3-phosphorylcholine \| Phosphatidylcholines,soya \| Dimethyldioctadecylammonium (bromide) \| DMG-PEG 2000 \| 1,2-Dierucoyl-sn-glycero-3-PC \| DOTAP chloride \| DODAP \| Stearamide
相關(guān)庫	經(jīng)典已知活性庫 \| 已知活性化合物庫 \| 活性脂質(zhì)化合物庫 \| NO PAINS 化合物庫 \| 抗COVID-19化合物庫

關(guān)鍵字： D-Lin-MC3-DMA;TargetMol

公司簡介

上海陶術(shù)生物科技有限公司為美國Target Molecule Corp. ( Target Mol ) 在上海建立的全資子公司。我們與美國波士頓、德國慕尼黑的同事一起，為北美、歐洲和亞洲從事藥物研發(fā)和生物學(xué)研究的科學(xué)家提供優(yōu)質(zhì)的產(chǎn)品和專業(yè)的服務(wù)。公司下設(shè)篩選事業(yè)部，化學(xué)事業(yè)部，生物事業(yè)部和新材料部。從虛擬篩選到實(shí)體化合物分子供應(yīng)；從商業(yè)化產(chǎn)品銷售到個性化定制合成；從對明確靶點(diǎn)的分子篩選到對明確分子的多靶點(diǎn)篩選，從高通量篩選到化學(xué)結(jié)構(gòu)優(yōu)化，我們都可以滿足您的科研用品及技術(shù)服務(wù)的需求。經(jīng)過在中國市場五年的精心耕耘，我們已成為篩選化合物領(lǐng)域優(yōu)秀的供應(yīng)商，為超過五百家學(xué)校和各類企業(yè)提供了品質(zhì)卓越的小分子化合物和藥物篩

成立日期	2013-04-18 （14年）	注冊資本	566.2651萬人民幣
員工人數(shù)	100-500人	年?duì)I業(yè)額	￥ 1億以上
主營行業(yè)	化學(xué)試劑,生物活性小分子	經(jīng)營模式	貿(mào)易,試劑,定制,服務(wù)

TargetMol中國（陶術(shù)生物）

VIP 14年

公司成立：14年
注冊資本：566.2651萬人民幣
企業(yè)類型：有限責(zé)任公司(自然人投資或控股)
主營產(chǎn)品：小分子抑制劑，藥物篩選化合物庫，天然產(chǎn)物，活性分子化合物等
公司地址：上海市閘北區(qū)江場三路28號4樓

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