夫西地酸鈉|T1289

2篇文獻(xiàn)

價格	￥108	￥137	￥347
包裝	50mg	100mg	500mg

最小起訂量	50mg
發(fā)貨地	上海
更新日期	2026-08-03

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產(chǎn)品詳情

中文名稱:夫西地酸鈉	英文名稱:Fusidic acid sodium salt
CAS:751-94-0	品牌: TargetMol
產(chǎn)地: 美國	保存條件: Keep away from moisture, Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
純度規(guī)格: 99.81%	產(chǎn)品類別: 抑制劑
貨號: T006\|T1289

Product Introduction

Bioactivity

名稱	Fusidic acid sodium salt
描述	Fusidic acid sodium salt (SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
激酶實驗	Binding assays: Binding assays are performed as previously described (Allenby et al., 1993, 1994). Briefly, labeled and unlabeled retinoids are added to nucleosol or cytosolic fractions in ethanol so that the total amount of ethanol added is constant in all tubes and did not exceed 2% of the incubation volume. The receptor preparations are incubated with retinoids at 4°C for 4–6 hr. Sephadex PD-10 desalting columns are used to separate bound radioligand from free radioligand after equilib- rium is achieved. For competitive binding assays, varying concentrations of unlabeled competing ligand are incubated with the appropriate nucleosol or cytosol in the presence of a fixed concentration of [3H]tRA (sp. act. 49.3 Ci/mmol) or [3H]9-cis RA (sp. act. 24.0 Ci/mmol). Final concentrations of [3H] tRA and [3H]9-cis RA for nuclear receptor binding assays are 5 nM. Final concentrations of [3H] tRA for CRABP binding assays is 30 nM. The IC50s are calculated as described above (DeLean et al., 1978). For saturation kinetics, increasing concentrations of radiolabeled ligand ([3H]tRA sp. act. 49.3 Ci/mmol, [3H]TTNPB sp. act. 5.5 Ci/ mmol) are added to the nucleosol of the appropriate receptor subtype in the presence (nonspecific binding) or absence (total binding) of a 100-fold molar excess of the corresponding unlabeled retinoid. Specific binding is defined as the total binding minus nonspecific binding. Saturation kinetics are calculated as previously described (Scatchard, 1949; Grippo and Gudas, 1987; Levin et al., 1992).
體內(nèi)活性	Fusidin（Fusidate Sodium）至少在一定程度上通過抑制TNF-α的分泌改善EAM[1]。Fusidin顯著減輕了給予鏈脲佐菌素（SZ）的小鼠免疫炎癥糖尿病的臨床和組織學(xué)征象。該作用是劑量依賴性的，且在三個不同的小鼠品系中均有觀察到。因此，F(xiàn)usidin 可能具有抗糖尿病效應(yīng)[2]。
存儲條件	Keep away from moisture, Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
溶解度	Ethanol : 93 mg/mL (172.64 mM), Sonication is recommended. H2O : 92 mg/mL (170.78 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (6.13 mM), Sonication is recommended. DMSO : 93 mg/mL (172.64 mM), Sonication is recommended.
關(guān)鍵字	steroids \| SQ16360 \| SQ 16360 \| ribosome \| Inhibitor \| inhibit \| growth \| Fusidic acid sodium salt \| Fusidic acid sodium \| Fusidic acid \| factor \| elongation factor G (EF-G) \| elongation \| CAT \| bacteriostatic \| Bacterial \| Antibiotic
相關(guān)產(chǎn)品	Levulinic acid \| Doxycycline \| Neomycin sulfate \| Terbinafine hydrochloride \| Chitosan hydrochloride (80%-90% deacetylated) \| Dimethyl sulfoxide \| Gluconate Calcium \| Hyaluronic acid sodium (MW 20 kDa) \| Sodium diacetate \| Sulfamethoxazole sodium \| D(+)-Raffinose pentahydrate \| Hydroxypropyl Cellulose
相關(guān)庫	微生物天然產(chǎn)物庫 \| 抑制劑庫 \| 經(jīng)典已知活性庫 \| 已知活性化合物庫 \| 氧化還原化合物庫 \| 活性脂質(zhì)化合物庫 \| 抗菌活性庫 \| FDA上市及藥典收錄分子庫 \| NO PAINS 化合物庫 \| 免疫/炎癥分子化合物庫 \| 藥物功能重定位化合物庫 \| NMPA中國上市藥物庫

關(guān)鍵字：夫西地酸鈉;SQ-16360;Sodium fusidate;Fusidate Sodium;Fucidin;TargetMol

公司簡介

上海陶術(shù)生物科技有限公司為美國Target Molecule Corp. ( Target Mol ) 在上海建立的全資子公司。我們與美國波士頓、德國慕尼黑的同事一起，為北美、歐洲和亞洲從事藥物研發(fā)和生物學(xué)研究的科學(xué)家提供優(yōu)質(zhì)的產(chǎn)品和專業(yè)的服務(wù)。公司下設(shè)篩選事業(yè)部，化學(xué)事業(yè)部，生物事業(yè)部和新材料部。從虛擬篩選到實體化合物分子供應(yīng)；從商業(yè)化產(chǎn)品銷售到個性化定制合成；從對明確靶點的分子篩選到對明確分子的多靶點篩選，從高通量篩選到化學(xué)結(jié)構(gòu)優(yōu)化，我們都可以滿足您的科研用品及技術(shù)服務(wù)的需求。經(jīng)過在中國市場五年的精心耕耘，我們已成為篩選化合物領(lǐng)域優(yōu)秀的供應(yīng)商，為超過五百家學(xué)校和各類企業(yè)提供了品質(zhì)卓越的小分子化合物和藥物篩

成立日期	2013-04-18 （14年）	注冊資本	566.2651萬人民幣
員工人數(shù)	100-500人	年營業(yè)額	￥ 1億以上
主營行業(yè)	化學(xué)試劑,生物活性小分子	經(jīng)營模式	貿(mào)易,試劑,定制,服務(wù)

TargetMol中國（陶術(shù)生物）

VIP 14年

公司成立：14年
注冊資本：566.2651萬人民幣
企業(yè)類型：有限責(zé)任公司(自然人投資或控股)
主營產(chǎn)品：小分子抑制劑，藥物篩選化合物庫，天然產(chǎn)物，活性分子化合物等
公司地址：上海市閘北區(qū)江場三路28號4樓

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