Mouse Cadherin-6 / KCAD / CDH6 Protein, His Tag
分子別名（Synonym）
CDH6,CAD6,KCAD,K-cadherin,Cadherin-6
表達區(qū)間及表達系統(tǒng)（Source）
Mouse Cadherin-6, His Tag (CA6-M52H8) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Ala 615 (Accession # P97326-1).
Predicted N-terminus: Thr 19
蛋白結構（Molecular Characterization）
This protein carries a polyhistidine tag at the C-terminus. The Human Cadherin-6 will be further processed into mature form (Ser 54 - Ala 615).
The protein has a calculated MW of 68.3 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
純度（Purity）
>95% as determined by SDS-PAGE.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景（Background）
鈣粘蛋白-6（CDH6）也稱為腎鈣粘蛋白（K-Cadherin或KCAD），是鈣粘蛋白超家族中的一種II型經(jīng)典鈣粘蛋白。鈣粘蛋白是鈣依賴性細胞粘附蛋白。它們在連接細胞時優(yōu)先以親同的方式與自己相互作用；鈣粘蛋白因此可能有助于異質細胞類型的分選。CDH6/KCAD包含五個鈣粘蛋白結構域。CDH6在大腦、小腦和腎臟中高度表達。肺、胰腺和胃黏膜的表達較弱，在某些肝癌和腎癌中也有表達。
關鍵字： Cadherin-6;Cadherin-6蛋白;Cadherin-6蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group（股票代碼：301080）是成立于2010年的跨國生物科技公司，是為全球生物醫(yī)藥、健康產業(yè)領域提供關鍵生物試劑產品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球，橫跨亞洲、北美洲、歐洲，在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產基地。目前累計服務客戶超6000家，與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。