2-二環(huán)己基磷-2',4',6'-三異丙基聯(lián)苯是一種由Buchwald集團開發(fā)的空氣穩(wěn)定的富電子聯(lián)芳基單膦配體2，以增強在交叉偶聯(lián)反應過程中提高鈀催化的反應性。 1、用于深入研究芳烴磺酸酯、芳基鹵的鈀催化胺化和酰胺化反應的配體； 2、用作鈀催化 Suzuki 偶聯(lián)反應的配體，生成文朵靈的 C-15 類似物； 3、用于鈀催化 2-鹵代苯胺直接環(huán)化生成吲哚和色氨酸。區(qū)域規(guī)則性聚噻吩的合成。

It is a ligand for increased scope of Pd-catalyzed amination and amidation via arene sulfonates, aryl halides. It is a ligand used in a Pd-catalyzed Suzuki coupling leading to C-15 analogs of vindoline and direct annulation of 2-haloanilines to indoles and tryptophans.
Preferred ligand for greener Sonogashira coupling in TPGS-750-M. It may be used as a ligand in the following reactions: ? Preparation of functionalized benzylic sulfones via palladium-catalyzed Negishi cross-coupling between alkyl sulfones and aryl halides. ? Along with pre-milled palladium(II) acetate as a pre-catalyst for the Stille cross-coupling of aryl chlorides with tributylarylstannanes to form the corresponding biaryl compounds. ?Along with platinum chloride to catalyze the hydrosilylation of terminal arylalkynes with silanes to form functionalized β-(E)-vinylsilanes