Human FGF-7 / HBGF-7 / KGF Protein, premium grade
分子別名（Synonym）
FGF-7,Fibroblast growth factor 7,HBGF-7,Keratinocyte growth factor,KGF
表達區(qū)間及表達系統(tǒng)（Source）
Human FGF-7 Protein, premium grade (FG7-H5213) is expressed from human 293 cells (HEK293). It contains AA Cys 32 - Thr 194 (Accession # P21781-1).
該產(chǎn)品是在我們嚴格的質(zhì)量控制體系下生產(chǎn)的，該體系包含一套全面的測試，包括無菌和內(nèi)毒素測試。在早期臨床前階段，產(chǎn)品性能經(jīng)過仔細驗證和測試，以確保其與細胞培養(yǎng)用途或任何其他應用的兼容性。當準備過渡到后期臨床階段時，我們還提供定制的GMP蛋白質(zhì)服務，以滿足您的需求。我們將與您合作，根據(jù)您的要求定制和開發(fā)GMP級產(chǎn)品，該產(chǎn)品也符合細胞療法細胞制造中使用的原材料和輔助材料的要求。
蛋白結(jié)構（Molecular Characterization）
This protein carries no "tag".
The protein has a calculated MW of 19.0 kDa. The protein migrates as 27 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素（Endotoxin）
Less than 0.01 EU per μg by the LAL method.
宿主蛋白殘留（Host Cell Protein）
<0.5 ng/μg of protein tested by ELISA.
宿主核酸殘留（Host Cell DNA）
<0.02 ng/μg of protein tested by qPCR.
無菌（Sterility）
Negative
支原體（Mycoplasma）
Negative.
純度（Purity）
>95% as determined by SDS-PAGE.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 24 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景（Background）
Fibroblast growth factor (FGF) 7 (is also known as Keratinocyte growth factor (KGF)), a member of FGF family, is initially found to be secreted from mesenchymal cells to repair epithelial tissues. As a well-characterized paracrine growth factor for tissue growth and regeneration, fibroblast growth factor 7 (FGF7) is involved in a number of physiological and pathological processes, including lung disease and cancer. The stromal-derived FGFs, such as FGF7 and FGF10, control epithelial cell resident FGFR2IIIb activities, promote net tissue homeostasis, and restraint tumor cells from progression to malignancy.
關鍵字： FGF-7;FGF-7蛋白;FGF-7重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group（股票代碼：301080）是成立于2010年的跨國生物科技公司，是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領域提供關鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球，橫跨亞洲、北美洲、歐洲，在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家，與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。