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CARM1抗體,Mouse Monoclonal CARM1 Antibody
  • CARM1抗體,Mouse Monoclonal CARM1 Antibody
  • CARM1抗體,Mouse Monoclonal CARM1 Antibody
  • CARM1抗體,Mouse Monoclonal CARM1 Antibody

CARM1抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-09
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CARM1抗體英文名稱:Mouse Monoclonal CARM1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 363 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Mouse
偶聯(lián)物: 靶點: CARM1
2025-05-09 CARM1抗體 Mouse Monoclonal CARM1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 363 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB1/500 - 1/2000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/200 - 1/1000 Human,Mouse,Rat
ICC1/200 - 1/1000 Human,Mouse,Rat
FCM1/200 - 1/400 Human,Mouse,Rat
Elisa1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesPRMT4; CARM1
Entrez GeneID10498
clone3H2
WB Predicted band size65kDa
Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat,Rabbit,Monkey
ImmunogenPurified recombinant fragment of human CARM1 expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide.

+ +

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       Western blot analysis using CARM1 mouse mAb against MCF-7 (1), Hela (2), NIH/3T3 (3), HL-60 (4), LNcap (5), Jurkat (6), PC-3 (7), Cos7 (8), and PC-12 (9) cell lysate.    


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       Western blot analysis using CARM1 mouse mAb against CHO3D10(1),COS-7(2),F9(3),L1210(4),C2C12(5),NIH/3T3(6),Mouse liver(7) cell lysate.    


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       Immunofluorescence analysis of Hela cells using CRAM1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.    


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       Flow cytometric analysis of Lovo cells using CARM1 mouse mAb (green) and negative control (purple).    


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       Flow cytometric analysis of Hela cells using CARM1 mouse mAb (green) and negative control (red).    


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       Flow cytometric analysis of NIH/3T3 cells using CARM1 mouse mAb (green) and negative control (red).    


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       Flow cytometric analysis of COS7 cells using CARM1 mouse mAb (green) and negative control (red).    


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       Immunohistochemical analysis of paraffin-embedded human breast cancer tissues (left) and ovarian cancer tissues (right) using CARM1 mouse mAb with DAB staining.    


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       Immunohistochemical analysis of paraffin-embedded Mouse brain(A)Mouse kidney(B) using CARM1 mouse mAb with DAB staining.    


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       Immunohistochemical analysis of paraffin-embedded Rat brain(A) Rat kidney(B) using CARM1 mouse mAb with DAB staining.    


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       Immunohistochemical analysis of paraffin-embedded Rabbit (A)Rabbit kidney(B) using CARM1 mouse mAb with DAB staining.    


           

參考文獻

以下是關(guān)于CARM1抗體的3篇示例參考文獻(注:文獻為假設(shè)性示例,非真實存在):

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1. **文獻名稱**: "CARM1-Mediated Methylation in Breast Cancer Progression"

**作者**: Smith A, et al.

**摘要**: 本研究利用特異性CARM1抗體,通過免疫印跡和免疫組化分析,揭示CARM1在乳腺癌中通過甲基化組蛋白H3R17促進腫瘤侵襲和轉(zhuǎn)移的機制。

2. **文獻名稱**: "CARM1 Antibody Validation for Epigenetic Studies"

**作者**: Lee J, et al.

**摘要**: 文章報道了一種高特異性CARM1抗體的開發(fā)與驗證,證明其在染色質(zhì)免疫沉淀(ChIP)和免疫熒光中的應(yīng)用,用于研究CARM1在基因轉(zhuǎn)錄調(diào)控中的作用。

3. **文獻名稱**: "CARM1 Regulates Adipogenesis via PPARγ Coactivation"

**作者**: Zhang Y, et al.

**摘要**: 使用CARM1抗體進行敲低實驗,發(fā)現(xiàn)CARM1通過甲基化修飾PPARγ共激活因子,調(diào)控脂肪細胞分化和代謝相關(guān)基因表達。

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如需真實文獻,建議通過PubMed或Google Scholar搜索關(guān)鍵詞 **CARM1 antibody** 或 **CARM1 (PRMT4)**,并篩選涉及抗體應(yīng)用的研究。

       

背景信息

**Background of CARM1 Antibody**

CARM1 (Coactivator-Associated Arginine Methyltransferase 1), also known as PRMT4. is a member of the protein arginine methyltransferase (PRMT) family. It catalyzes the methylation of arginine residues on histones and non-histone proteins, playing a critical role in transcriptional regulation, chromatin remodeling, and cellular signaling. CARM1 functions as a coactivator for nuclear receptors (e.g., estrogen and androgen receptors) and transcription factors, facilitating gene activation by modifying histones (e.g., H3R17 and H3R26 methylation) and methylating transcriptional regulators like p300 and MED12.

CARM1 antibodies are essential tools for studying its expression, localization, and molecular interactions. They are widely used in techniques such as Western blotting, immunoprecipitation, and immunofluorescence to investigate CARM1's role in development, differentiation, and disease. Dysregulation of CARM1 is linked to cancers, inflammatory disorders, and metabolic syndromes, making it a potential therapeutic target. Antibodies specific to CARM1 help validate its involvement in pathways like the p53 network, Wnt/β-catenin signaling, and immune responses. Researchers rely on these antibodies to explore CARM1's dual role as an oncogene or tumor suppressor, depending on cellular context, and its impact on splicing, cell cycle, and apoptosis. Validated CARM1 antibodies are crucial for advancing studies in epigenetics and disease mechanisms.

       
關(guān)鍵字: CARM1抗體;CARM1;CARM1 Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學(xué)試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
普通會員
  • 公司成立:2年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

CARM1抗體相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP7年
上海澤葉生物科技有限公司
2026-06-09
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
詢價
VIP6年
上海冠導(dǎo)生物工程有限公司
2026-06-09
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