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CTSV抗體,Rabbit Polyclonal CTSV Antibody
  • CTSV抗體,Rabbit Polyclonal CTSV Antibody
  • CTSV抗體,Rabbit Polyclonal CTSV Antibody
  • CTSV抗體,Rabbit Polyclonal CTSV Antibody

CTSV抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-11
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CTSV抗體英文名稱:Rabbit Polyclonal CTSV Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 1639 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: CTSV
2025-05-11 CTSV抗體 Rabbit Polyclonal CTSV Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 1639 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB1/500-1/2000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesCTSU; CATL2; CTSL2
WB Predicted band size37 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human CTSV
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Jurkat cell, Mouse placenta tissue lysates, Primary antibody: P00239(CTSV Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P00239(CTSV Antibody) at dilution 1/50. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P00239(CTSV Antibody) at dilution 1/50. (Original magnification: ×200)    


           

參考文獻

以下是關(guān)于CTSV抗體的3篇參考文獻示例(注:以下內(nèi)容為模擬生成,實際文獻需通過學(xué)術(shù)數(shù)據(jù)庫查詢):

1. **文獻名稱**:*"Development of a Monoclonal Antibody Specific for Cathepsin V and Its Application in Immunohistochemical Analysis"*

**作者**:Johnson, R. et al.

**摘要**:該研究開發(fā)了一種針對CTSV(組織蛋白酶V)的高特異性單克隆抗體,驗證了其在免疫組織化學(xué)(IHC)中的應(yīng)用。實驗表明,該抗體能有效區(qū)分CTSV與同源蛋白CTSL,并在卵巢癌組織中檢測到CTSV的異常高表達。

2. **文獻名稱**:*"Cathepsin V as a Prognostic Biomarker in Triple-Negative Breast Cancer: Insights from Antibody-Based Detection"*

**作者**:Lee, S. & Martinez, A.

**摘要**:通過抗CTSV抗體進行Western blot和免疫熒光分析,研究發(fā)現(xiàn)CTSV在三陰性乳腺癌(TNBC)中顯著上調(diào),其表達水平與患者生存率負相關(guān),提示其作為預(yù)后標志物的潛力。

3. **文獻名稱**:*"Structural Characterization of Cathepsin V Using Antibody Epitope Mapping"*

**作者**:Zhang, Y. et al.

**摘要**:利用抗CTSV抗體的表位定位技術(shù),解析了CTSV的關(guān)鍵功能結(jié)構(gòu)域,揭示了其底物結(jié)合特異性機制,為開發(fā)靶向CTSV的抑制劑提供了結(jié)構(gòu)學(xué)依據(jù)。

**提示**:實際研究中建議通過PubMed、Web of Science等平臺,以關(guān)鍵詞“CTSV antibody”、“Cathepsin V antibody”或結(jié)合具體應(yīng)用(如“CTSV cancer biomarker”)檢索最新文獻。

       

背景信息

The CTSV antibody targets Cathepsin V (CTSV), a lysosomal cysteine protease belonging to the papain-like protease family. Also known as Cathepsin L2. CTSV shares structural and functional similarities with Cathepsin L but exhibits distinct substrate specificity and tissue expression patterns. It is primarily expressed in thymic epithelial cells, corneal epithelium, and certain immune cells, playing roles in antigen processing, extracellular matrix remodeling, and cellular homeostasis. CTSV is synthesized as an inactive proenzyme that undergoes proteolytic cleavage in acidic environments to become an active protease.

Research highlights CTSV's involvement in pathological conditions, including cancer, autoimmune disorders, and inflammatory diseases. Overexpression of CTSV has been observed in melanoma, breast cancer, and rheumatoid arthritis, where it contributes to tissue invasion, metastasis, and chronic inflammation by degrading collagen and other structural proteins. CTSV antibodies are vital tools for detecting its expression and localization in tissues or cell cultures, facilitating studies on its biological functions and disease associations. These antibodies are widely used in techniques like Western blotting, immunohistochemistry, and flow cytometry. Additionally, CTSV is explored as a potential therapeutic target, with inhibitors under investigation for modulating its activity in disease contexts. Its dual role in physiological processes and pathology makes CTSV a compelling subject for biomedical research.

       
關(guān)鍵字: CTSV抗體;CTSV;CTSV Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學(xué)試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
普通會員
  • 公司成立:2年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

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