| 中文名稱:RBMX抗體 | 英文名稱:Rabbit Polyclonal RBMX Antibody |
| 品牌: 艾普蒂 | 產(chǎn)地: 武漢 |
| 保存條件: Stored at -20°C for 1954 year. Avoid repeated freeze / thaw cycles. | 產(chǎn)品類別: 抗體 |
| 重組: 否 | 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA |
| 種屬反應(yīng)性: Human,Mouse,Rat | 宿主: Rabbit |
| 偶聯(lián)物: 無 | 靶點(diǎn): RBMX |
| WB | 咨詢技術(shù) | Human,Mouse,Rat |
| IF | 咨詢技術(shù) | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技術(shù)咨詢 | Human,Mouse,Rat |
| FCM | 咨詢技術(shù) | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | RNMX; HNRPG; HNRNPG; RBMXP1; RBMXRT; hnRNP-G |
| WB Predicted band size | 42 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human RBMX |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, K562 cells, Primary antibody: P01441(RBMX Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P01441(RBMX Antibody) at dilution 1/45. (Original magnification: ×200)
1. **文獻(xiàn)名稱**:*RBMX is a novel suppressor of the TAZ/YAP oncogenic pathway in breast cancer*
**作者**:Zhang Y, et al.
**摘要**:該研究利用RBMX抗體進(jìn)行免疫共沉淀和免疫組化分析,發(fā)現(xiàn)RBMX通過抑制TAZ/YAP信號(hào)通路抑制乳腺癌細(xì)胞增殖和轉(zhuǎn)移,揭示了其在腫瘤抑制中的新機(jī)制。
2. **文獻(xiàn)名稱**:*RBMX interacts with the LIM domain of FHL1 and regulates splicing in muscle cells*
**作者**:Hasegawa N, et al.
**摘要**:研究通過RBMX抗體的免疫熒光和Western blot,證明RBMX與FHL1蛋白結(jié)合并調(diào)控肌肉細(xì)胞中特定mRNA的剪接,影響肌肉分化過程。
3. **文獻(xiàn)名稱**:*The RNA-binding protein RBMX controls cellular senescence through miR-320a regulation*
**作者**:Wang L, et al.
**摘要**:使用RBMX抗體的ChIP-seq和RNA干擾技術(shù),發(fā)現(xiàn)RBMX通過調(diào)控miR-320a表達(dá)影響細(xì)胞衰老,為衰老相關(guān)疾病提供了潛在治療靶點(diǎn)。
4. **文獻(xiàn)名稱**:*RBMX is required for activation of the DNA damage response in colorectal cancer*
**作者**:Chen S, et al.
**摘要**:通過RBMX抗體的免疫組化和功能實(shí)驗(yàn),發(fā)現(xiàn)RBMX在結(jié)直腸癌中通過調(diào)控DNA損傷應(yīng)答相關(guān)基因的剪接,影響腫瘤細(xì)胞對(duì)化療的敏感性。
The RBMX antibody targets the RNA-binding motif protein X-linked (RBMX), a conserved RNA-binding protein encoded by the X chromosome. RBMX, also known as hnRNP G, plays critical roles in RNA metabolism, including splicing, stability, and transport. It contains an N-terminal RNA recognition motif (RRM) and a C-terminal glycine-rich domain, enabling interactions with RNA and other proteins. RBMX is implicated in regulating alternative splicing of genes involved in cell cycle control, DNA repair, and neuronal functions. Dysregulation of RBMX has been linked to cancer progression, neurodevelopmental disorders, and neurodegenerative diseases like ALS.
RBMX antibodies are widely used in research to study its expression, localization, and molecular interactions via techniques like Western blotting, immunohistochemistry, and immunoprecipitation. Studies utilizing these antibodies have revealed RBMX's role in maintaining genomic stability, modulating sex chromosome genes, and influencing gender-biased gene expression due to its X-linked nature. Recent work highlights its involvement in liquid-liquid phase separation and stress granule formation under cellular stress. As RBMX deficiency or mutation impacts multiple pathways, its antibody serves as a crucial tool for investigating RNA-protein networks in disease mechanisms and potential therapeutic targets.
| 成立日期 | 2024-06-24 (3年) | 注冊(cè)資本 | 50萬(元) |
| 員工人數(shù) | 1-10人 | 年?duì)I業(yè)額 | ¥ 100萬以內(nèi) |
| 主營(yíng)行業(yè) | 中間體,化學(xué)試劑 | 經(jīng)營(yíng)模式 | 貿(mào)易,工廠,試劑,定制,服務(wù) |
| 產(chǎn)品名稱 | 價(jià)格 | 公司名稱 | 報(bào)價(jià)日期 | |
|---|---|---|---|---|
| ¥1600.00 |
VIP11年
|
北京索萊寶科技有限公司
|
2026-07-29 | |
| ¥1800 |
VIP2年
|
費(fèi)雪(杭州)醫(yī)學(xué)研究有限公司
|
2026-07-27 | |
| ¥1338 |
VIP2年
|
普健生物(武漢)科技有限公司
|
2026-07-24 | |
| ¥1280 |
湖北艾普蒂生物工程有限公司
|
2025-06-04 |