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CAMK1G抗體,Rabbit Polyclonal CAMK1G Antibody
  • CAMK1G抗體,Rabbit Polyclonal CAMK1G Antibody

CAMK1G抗體

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-12
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CAMK1G抗體英文名稱:Rabbit Polyclonal CAMK1G Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3398 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): CAMK1G
2025-05-12 CAMK1G抗體 Rabbit Polyclonal CAMK1G Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3398 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesVWS1; CLICK3; CLICKIII; dJ272L16.1
WB Predicted band size53 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human CAMK1G
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: P07148(CAMK1G Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1MIN    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07148(CAMK1G Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P07148(CAMK1G Antibody) at dilution 1/20. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于CAMK1G抗體的3篇參考文獻(xiàn)示例(內(nèi)容為模擬,非真實(shí)文獻(xiàn)):

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1. **文獻(xiàn)名稱**:*Characterization of CAMK1G Antibody Specificity in Neuronal Signaling Pathways*

**作者**:Smith A, et al.

**摘要**:本研究驗(yàn)證了一種新型抗CAMK1G抗體的特異性,通過Western blot和免疫熒光技術(shù)證明其在人腦組織及神經(jīng)元細(xì)胞系中的高選擇性。實(shí)驗(yàn)表明CAMK1G在鈣離子信號(hào)傳導(dǎo)中調(diào)控突觸可塑性,抗體成功用于檢測其磷酸化狀態(tài)。

2. **文獻(xiàn)名稱**:*CAMK1G Expression in Colorectal Cancer: An Immunohistochemical Study*

**作者**:Chen L, et al.

**摘要**:利用商業(yè)化CAMK1G抗體對結(jié)直腸癌組織進(jìn)行免疫組化分析,發(fā)現(xiàn)CAMK1G高表達(dá)與患者預(yù)后不良相關(guān),提示其可能作為腫瘤進(jìn)展的生物標(biāo)志物??贵w特異性通過siRNA敲低實(shí)驗(yàn)驗(yàn)證。

3. **文獻(xiàn)名稱**:*Development of a Monoclonal Antibody Targeting CAMK1G for Functional Studies*

**作者**:Yamamoto K, et al.

**摘要**:報(bào)道了一種高親和力CAMK1G單克隆抗體的開發(fā),該抗體適用于流式細(xì)胞術(shù)和免疫沉淀。研究證實(shí)CAMK1G在T細(xì)胞活化中調(diào)控NFAT信號(hào)通路,抗體成功用于體內(nèi)外功能抑制實(shí)驗(yàn)。

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注:以上內(nèi)容為示例,實(shí)際文獻(xiàn)需通過PubMed、Google Scholar等平臺(tái)檢索確認(rèn)。

       

背景信息

The CAMK1G antibody is a research tool designed to detect and quantify the calcium/calmodulin-dependent protein kinase 1G (CAMK1G), a member of the CAMK serine/threonine kinase family. CAMK1G is part of the CAMK1 subfamily, which includes kinases activated by calcium/calmodulin signaling. This enzyme plays a role in regulating cellular processes such as transcriptional activation, cell cycle progression, and hormone secretion by phosphorylating downstream targets. Structurally, CAMK1G contains a catalytic domain, an autoinhibitory regulatory domain, and a C-terminal extension that may influence subcellular localization and substrate specificity.

Expressed predominantly in the brain, testis, and endocrine tissues, CAMK1G is implicated in neural development, synaptic plasticity, and endocrine functions. Studies suggest its involvement in pathways linking calcium signaling to gene expression, often interacting with upstream activators like CAMKK and calmodulin. Dysregulation of CAMK1G has been explored in neurological disorders and metabolic syndromes, though its exact pathophysiological roles remain under investigation.

The CAMK1G antibody is widely used in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to study protein expression, localization, and activity in cellular or tissue samples. Researchers rely on its specificity to explore CAMK1G's interactions, activation mechanisms, and relevance in disease models. Validated antibodies are critical for distinguishing CAMK1G from homologous kinases, ensuring accuracy in experimental data. As calcium signaling pathways are central to numerous physiological and pathological processes, CAMK1G antibodies serve as essential tools for advancing understanding of cellular signaling networks.

       
關(guān)鍵字: CAMK1G抗體;CAMK1G;CAMK1G Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (3年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學(xué)試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
普通會(huì)員
  • 公司成立:3年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
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