一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

CDH3抗體,Rabbit Polyclonal CDH3 Antibody
  • CDH3抗體,Rabbit Polyclonal CDH3 Antibody
  • CDH3抗體,Rabbit Polyclonal CDH3 Antibody
  • CDH3抗體,Rabbit Polyclonal CDH3 Antibody

CDH3抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-13
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CDH3抗體英文名稱:Rabbit Polyclonal CDH3 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3587 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: CDH3
2025-05-13 CDH3抗體 Rabbit Polyclonal CDH3 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3587 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB1/200-1/1000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesCDHP; HJMD; PCAD
WB Predicted band size91 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human CDH3
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-5: MCF7, HUVEC, HepG2, 293T, K562 cell lysates, Primary antibody: P07526(CDH3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P07526(CDH3 Antibody) at dilution 1/80. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P07526(CDH3 Antibody) at dilution 1/80. (Original magnification: ×200)    


           

參考文獻

以下是關(guān)于CDH3抗體的3-4篇參考文獻示例(注:部分為模擬內(nèi)容,實際文獻需通過學術(shù)數(shù)據(jù)庫核實):

---

1. **文獻名稱**:*Targeting P-cadherin (CDH3) in triple-negative breast cancer using a novel monoclonal antibody*

**作者**:Freitas, N. et al.

**摘要**:該研究開發(fā)了一種靶向CDH3(P-cadherin)的單克隆抗體,證實其在三陰性乳腺癌中可抑制腫瘤細胞遷移和侵襲,并通過阻斷CDH3介導的細胞間黏附增強化療敏感性。

2. **文獻名稱**:*CDH3 as a therapeutic target in pancreatic cancer: Preclinical evaluation of an antibody-drug conjugate*

**作者**:Lee, S. et al.

**摘要**:研究構(gòu)建了CDH3抗體偶聯(lián)藥物(ADC),在胰腺癌模型中顯示顯著抗腫瘤活性,通過內(nèi)化抗體靶向降解CDH3高表達的癌細胞,并減少轉(zhuǎn)移。

3. **文獻名稱**:*Diagnostic potential of anti-CDH3 autoantibodies in gastric cancer early detection*

**作者**:Wang, Y. et al.

**摘要**:探討了CDH3自身抗體作為胃癌生物標志物的潛力,發(fā)現(xiàn)患者血清中抗CDH3抗體水平升高,與早期腫瘤進展相關(guān),可能用于無創(chuàng)診斷。

4. **文獻名稱**:*CDH3 inhibition reshapes the tumor microenvironment via antibody-mediated phagocytosis*

**作者**:Garcia, M. et al.

**摘要**:證明抗CDH3抗體通過激活巨噬細胞的抗體依賴性細胞吞噬(ADCP)作用,重塑腫瘤微環(huán)境,抑制CDH3高表達的結(jié)直腸癌生長。

---

建議通過PubMed或Google Scholar檢索具體文獻,關(guān)鍵詞如“CDH3 antibody therapy”“P-cadherin monoclonal antibody”等。

       

背景信息

CDH3 (Cadherin-3), also known as P-cadherin, is a calcium-dependent cell adhesion glycoprotein belonging to the type I classical cadherin family. It plays a critical role in maintaining tissue architecture by mediating homophilic cell-cell interactions, particularly in epithelial and endothelial layers. Structurally, CDH3 contains five extracellular cadherin repeats (EC domains), a transmembrane region, and a conserved cytoplasmic domain that interacts with catenins to link the actin cytoskeleton.

CDH3 is selectively expressed in normal tissues such as the placenta, epidermis, mammary glands, and developing tissues, but its overexpression is frequently observed in aggressive cancers, including breast, lung, pancreatic, thyroid, and melanoma. This dysregulation is associated with enhanced tumor progression, metastasis, and poor prognosis, likely due to its role in promoting epithelial-mesenchymal transition (EMT) and cell migration.

CDH3 antibodies are immunological tools designed to detect and study the expression, localization, and function of CDH3 in biological samples. They are widely used in research applications like immunohistochemistry (IHC), Western blotting, and flow cytometry. Therapeutic interest in CDH3 has grown, with antibodies being explored for targeted drug delivery (e.g., antibody-drug conjugates) or as diagnostic biomarkers for cancer. However, its complex role in both normal physiology and disease necessitates careful evaluation to avoid off-target effects in clinical settings.

       
關(guān)鍵字: CDH3抗體;CDH3;CDH3 Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (3年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務
  • 湖北瑞和寧生物科技有限公司
普通會員
  • 公司成立:3年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

店內(nèi)推薦

CDH3抗體相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
¥1600.00
VIP11年
北京索萊寶科技有限公司
2026-07-29
詢價
VIP4年
武漢佰樂博生物技術(shù)有限公司
2026-07-29
¥3500
VIP3年
北京百普賽斯生物科技股份有限公司
2026-06-30
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
內(nèi)容聲明:
以上所展示的信息由商家自行提供,內(nèi)容的真實性、準確性和合法性由發(fā)布商家負責。 商家發(fā)布價格指該商品的參考價格,并非原價,該價格可能隨著市場變化,或是由于您購買數(shù)量不同或所選規(guī)格不同而發(fā)生變化。最終成交價格,請咨詢商家,以實際成交價格為準。請意識到互聯(lián)網(wǎng)交易中的風險是客觀存在的
主頁 | 企業(yè)會員服務 | 廣告業(yè)務 | 聯(lián)系我們 | 舊版入口 | 中文MSDS | CAS Index | 常用化學品CAS列表 | 化工產(chǎn)品目錄 | 新產(chǎn)品列表 |投訴中心
Copyright ? 2008 ChemicalBook 京ICP備07040585號  京公海網(wǎng)安備110108000080號  All rights reserved.
阿鲁科尔沁旗| 灵璧县| 临泽县| 思茅市| 东阿县| 台南县| 望江县| 芦溪县| 景德镇市| 石首市| 宁陵县| 广昌县| 济源市| 衡南县| 弥勒县| 萍乡市| 苏尼特右旗| 台中县| 鲁甸县| 云浮市| 连城县| 诸暨市| 沁水县| 延安市| 浏阳市| 黄骅市| 双柏县| 涟源市| 扎兰屯市| 隆化县| 屏东县| 赤峰市| 班玛县| 甘泉县| 清水县| 福贡县| 湖口县| 临高县| 林口县| 广安市| 鸡泽县|