一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

PGC抗體,Rabbit Polyclonal PGC Antibody
  • PGC抗體,Rabbit Polyclonal PGC Antibody
  • PGC抗體,Rabbit Polyclonal PGC Antibody
  • PGC抗體,Rabbit Polyclonal PGC Antibody

PGC抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-13
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:PGC抗體英文名稱:Rabbit Polyclonal PGC Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3594 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: PGC
2025-05-13 PGC抗體 Rabbit Polyclonal PGC Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3594 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB1/500-1/2000 Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesPEPC, PGII
WB Predicted band size42 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human PGC
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 12%SDS-PAGE, Lysate: 50 μg, Lane: 823 cells, Primary antibody: P07538(PGC Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P07538(PGC Antibody) at dilution 1/20. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07538(PGC Antibody) at dilution 1/20. (Original magnification: ×200)    


           

參考文獻

以下是3篇與PGC(通常指PGC-1α)抗體相關(guān)的高影響力文獻摘要概括:

1. **《Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres》**

- **作者**: Lin, J., Wu, H., Tarr, P.T., et al.

- **摘要**: 該研究通過PGC-1α抗體檢測其在骨骼肌中的表達,發(fā)現(xiàn)PGC-1α過表達促進慢肌纖維形成,并增強線粒體功能,為肌肉代謝適應(yīng)機制提供關(guān)鍵證據(jù)。

2. **《Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1α null mice》**

- **作者**: Leone, T.C., Lehman, J.J., Finck, B.N., et al.

- **摘要**: 利用PGC-1α基因敲除小鼠模型,通過免疫印跡和免疫組化分析,揭示PGC-1α缺失導致中樞神經(jīng)系統(tǒng)能量代謝異常及線粒體功能紊亂,抗體檢測證實其在中樞神經(jīng)系統(tǒng)的特異性表達。

3. **《PGC-1α rescues Huntington’s disease proteotoxicity by preventing oxidative stress and enhancing TFEB function》**

- **作者**: Tsunemi, T., Ashe, T.D., Morrison, B.E., et al.

- **摘要**: 研究采用PGC-1α抗體檢測亨廷頓病模型中蛋白聚集情況,表明PGC-1α通過激活抗氧化通路和增強自噬緩解神經(jīng)退行性病變,抗體數(shù)據(jù)支持其作為治療靶點的潛力。

(注:若需具體抗體品牌或應(yīng)用細節(jié),需結(jié)合文獻方法部分進一步篩選。)

       

背景信息

PGC (Peroxisome Proliferator-Activated Receptor Gamma Coactivator) antibodies are essential tools for studying the PGC family of transcriptional coactivators, primarily PGC-1α, PGC-1β, and PRC. These proteins play pivotal roles in regulating mitochondrial biogenesis, energy metabolism, and adaptive thermogenesis by interacting with nuclear receptors and transcription factors. PGC-1α, the most studied member, is a master regulator of cellular energy homeostasis, influencing oxidative phosphorylation, gluconeogenesis, and fatty acid oxidation. Dysregulation of PGC-1α is linked to metabolic disorders (e.g., diabetes, obesity), neurodegenerative diseases (e.g., Alzheimer’s, Parkinson’s), and cancer.

PGC antibodies enable detection and quantification of these proteins in various experimental models, including Western blotting, immunohistochemistry, and immunofluorescence. They are critical for investigating tissue-specific expression patterns, such as high PGC-1α levels in metabolically active tissues (muscle, liver, brown adipose) or its suppression in pathological conditions. Researchers also use these antibodies to explore therapeutic interventions targeting mitochondrial dysfunction or metabolic syndromes.

Commercially available PGC antibodies are typically developed in rabbits or mice, with validation via knockout controls to ensure specificity. Challenges include cross-reactivity due to homologous domains among PGC family members, necessitating careful antibody selection. Recent studies emphasize PGC-1α’s role in aging and exercise-induced metabolic adaptation, underscoring the antibody’s relevance in translational research. Overall, PGC antibodies remain indispensable for dissecting molecular pathways governing energy metabolism and disease mechanisms.

       
關(guān)鍵字: PGC抗體;PGC;PGC Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (3年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
普通會員
  • 公司成立:3年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

店內(nèi)推薦

PGC抗體相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
¥1098
VIP4年
上海滬震實業(yè)有限公司
2026-07-24
¥960.00
VIP11年
北京索萊寶科技有限公司
2026-07-23
詢價
VIP4年
武漢佰樂博生物技術(shù)有限公司
2026-07-24
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
內(nèi)容聲明:
以上所展示的信息由商家自行提供,內(nèi)容的真實性、準確性和合法性由發(fā)布商家負責。 商家發(fā)布價格指該商品的參考價格,并非原價,該價格可能隨著市場變化,或是由于您購買數(shù)量不同或所選規(guī)格不同而發(fā)生變化。最終成交價格,請咨詢商家,以實際成交價格為準。請意識到互聯(lián)網(wǎng)交易中的風險是客觀存在的
主頁 | 企業(yè)會員服務(wù) | 廣告業(yè)務(wù) | 聯(lián)系我們 | 舊版入口 | 中文MSDS | CAS Index | 常用化學品CAS列表 | 化工產(chǎn)品目錄 | 新產(chǎn)品列表 |投訴中心
Copyright ? 2008 ChemicalBook 京ICP備07040585號  京公海網(wǎng)安備110108000080號  All rights reserved.
长春市| 遵义市| 锡林郭勒盟| 尉氏县| 逊克县| 邢台县| 林甸县| 灵璧县| 襄樊市| 湖南省| 镶黄旗| 通许县| 皮山县| 武山县| 宿松县| 鹤岗市| 灵璧县| 锡林浩特市| 武川县| 车险| 竹山县| 樟树市| 海伦市| 芮城县| 阆中市| 连州市| 武汉市| 宜昌市| 花莲县| 禹州市| 涟水县| 罗甸县| 土默特左旗| 洪洞县| 江陵县| 察哈| 利津县| 克拉玛依市| 古丈县| 玉龙| 清镇市|