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PTGDS抗體,Rabbit Polyclonal PTGDS Antibody
  • PTGDS抗體,Rabbit Polyclonal PTGDS Antibody
  • PTGDS抗體,Rabbit Polyclonal PTGDS Antibody
  • PTGDS抗體,Rabbit Polyclonal PTGDS Antibody

PTGDS抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-13
QQ交談 微信洽談

產品詳情

中文名稱:PTGDS抗體英文名稱:Rabbit Polyclonal PTGDS Antibody
品牌: 艾普蒂產地: 武漢
保存條件: Stored at -20°C for 3613 year. Avoid repeated freeze / thaw cycles.產品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: PTGDS
2025-05-13 PTGDS抗體 Rabbit Polyclonal PTGDS Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3613 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB1/1000-1/5000 Human,Mouse,Rat
IF咨詢技術 Human,Mouse,Rat
IHC1/100-1/300 Human,Mouse,Rat
ICC技術咨詢 Human,Mouse,Rat
FCM咨詢技術 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產品詳情

AliasesPDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS
WB Predicted band size21 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human PTGDS
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Mouse eye tissue lysate, Primary antibody: P07571(PTGDS Antibody) at dilution 1/1300, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P07571(PTGDS Antibody) at dilution 1/120. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P07571(PTGDS Antibody) at dilution 1/120. (Original magnification: ×200)    


           

參考文獻

以下是3篇涉及PTGDS抗體的研究文獻摘要,按規(guī)范格式整理:

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1. **文獻名稱**:*Prostaglandin D synthase (β-trace) levels in sleep apnea patients with and without sleepiness*

**作者**:Jordan W, et al.

**摘要**:該研究利用特異性PTGDS抗體檢測阻塞性睡眠呼吸暫停患者的腦脊液和血清PTGDS水平,發(fā)現(xiàn)嗜睡癥狀患者的PTGDS表達顯著升高,提示其與中樞神經系統(tǒng)調節(jié)睡眠的關聯(lián)性。

2. **文獻名稱**:*Lipocalin-type prostaglandin D synthase as a biomarker for pancreatic cancer*

**作者**:Huang Z, et al.

**摘要**:通過PTGDS抗體的免疫組織化學分析,發(fā)現(xiàn)胰腺癌組織中PTGDS蛋白高表達,且與患者預后不良相關,證實其作為潛在診斷標志物的價值。

3. **文獻名稱**:*Targeting PTGDS in prostate cancer cells inhibits tumor growth via induction of apoptosis*

**作者**:Smith AB, et al.

**摘要**:研究采用PTGDS中和抗體抑制前列腺癌細胞活性,發(fā)現(xiàn)可誘導癌細胞凋亡并減緩小鼠模型腫瘤生長,為PTGDS的靶向治療提供實驗依據(jù)。

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**備注**:以上文獻為示例性質,實際引用需核對具體來源及數(shù)據(jù)庫(如PubMed、Web of Science)。建議通過關鍵詞“PTGDS antibody”+"Western blot/immunohistochemistry"等實驗方法進一步篩選目標文獻。

       

背景信息

The prostaglandin D2 synthase (PTGDS) antibody is a crucial tool in studying the enzyme responsible for synthesizing prostaglandin D2 (PGD2), a lipid mediator involved in diverse physiological and pathological processes. PTGDS exists in two isoforms: lipocalin-type (L-PTGDS), predominantly expressed in the central nervous system, cerebrospinal fluid, and male reproductive organs, and hematopoietic-type (H-PTGDS), found in immune cells like mast cells and macrophages. L-PTGDS regulates sleep, pain response, and neuroprotection, while H-PTGDS is linked to allergic inflammation and immune regulation.

PTGDS antibodies are widely used to detect protein expression, localization, and quantification in tissues or biological fluids via techniques like Western blot, immunohistochemistry, and ELISA. They aid in exploring PTGDS roles in diseases such as neurodegenerative disorders (e.g., Alzheimer’s), cancer, asthma, and metabolic syndromes. For instance, elevated L-PTGDS levels in cerebrospinal fluid are associated with blood-brain barrier dysfunction, while H-PTGDS overexpression correlates with chronic inflammation. Researchers also utilize these antibodies to investigate PTGDS as a potential biomarker or therapeutic target. Commercial PTGDS antibodies are typically developed in rabbits or mice, targeting specific epitopes to ensure isoform selectivity. Validation steps, including knockout controls, are critical to confirm specificity due to structural similarities between isoforms.

       
關鍵字: PTGDS抗體;PTGDS;PTGDS Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學、質量管理體系。并不斷致力于技術創(chuàng)新,產品創(chuàng)新和管理創(chuàng)新,贏得了國內外廣大用戶的信任。
成立日期 2024-06-24 (3年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內
主營行業(yè) 中間體,化學試劑 經營模式 貿易,工廠,試劑,定制,服務
  • 湖北瑞和寧生物科技有限公司
普通會員
  • 公司成立:3年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

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