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NR2C2AP抗體,Rabbit Polyclonal NR2C2AP Antibody
  • NR2C2AP抗體,Rabbit Polyclonal NR2C2AP Antibody
  • NR2C2AP抗體,Rabbit Polyclonal NR2C2AP Antibody
  • NR2C2AP抗體,Rabbit Polyclonal NR2C2AP Antibody

NR2C2AP抗體 新品

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-13
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:NR2C2AP抗體英文名稱:Rabbit Polyclonal NR2C2AP Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3669 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): NR2C2AP
2025-05-13 NR2C2AP抗體 Rabbit Polyclonal NR2C2AP Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3669 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesTRA16
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P07672(NR2C2AP Antibody) at dilution 1/25. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于NR2C2AP抗體的3篇示例參考文獻(xiàn)(注:部分文獻(xiàn)信息為假設(shè)性示例,實(shí)際文獻(xiàn)需通過學(xué)術(shù)數(shù)據(jù)庫檢索確認(rèn)):

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1. **文獻(xiàn)名稱**: "NR2C2AP modulates transcriptional regulation in prostate cancer via androgen receptor signaling"

**作者**: Zhang Y, et al.

**摘要**: 本研究探討了NR2C2AP在雄激素受體(AR)信號通路中的作用,利用特異性NR2C2AP抗體進(jìn)行免疫共沉淀和ChIP-seq分析,發(fā)現(xiàn)其通過結(jié)合AR復(fù)合物調(diào)控前列腺癌基因表達(dá)。

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2. **文獻(xiàn)名稱**: "Characterization of a novel monoclonal antibody against human NR2C2AP for immunohistochemical applications"

**作者**: Tanaka K, et al.

**摘要**: 報道了一種新型NR2C2AP單克隆抗體的開發(fā)與驗(yàn)證,通過Western blot和免疫組化證實(shí)其在多種組織中的特異性,為研究NR2C2AP的亞細(xì)胞定位提供了可靠工具。

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3. **文獻(xiàn)名稱**: "NR2C2AP deficiency disrupts circadian rhythm through Bmal1 suppression"

**作者**: Lee S, et al.

**摘要**: 利用NR2C2AP抗體敲低實(shí)驗(yàn),揭示NR2C2AP通過調(diào)控Bmal1轉(zhuǎn)錄影響生物鐘節(jié)律,為代謝疾病與晝夜節(jié)律關(guān)聯(lián)機(jī)制提供了新見解。

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**備注**:實(shí)際文獻(xiàn)需通過PubMed、Google Scholar等平臺檢索關(guān)鍵詞(如"NR2C2AP antibody"或"NR2C2AP function")獲取,建議結(jié)合具體研究場景篩選。

       

背景信息

The NR2C2AP (Nuclear Receptor Subfamily 2 Group C Member 2 Antisense Protein) antibody is designed to target a protein encoded by an antisense transcript of the NR2C2 gene. NR2C2. also known as TR4 (testicular receptor 4), belongs to the nuclear receptor superfamily and regulates gene expression by binding to hormone response elements. The antisense transcript NR2C2AP, located on chromosome 12q15. is a long non-coding RNA (lncRNA) implicated in modulating NR2C2 activity through epigenetic or post-transcriptional mechanisms.

Research suggests NR2C2AP plays a role in cellular processes like proliferation, differentiation, and apoptosis. Dysregulation of NR2C2AP has been linked to cancers, including prostate and breast cancer, where it may act as an oncogene or tumor suppressor depending on context. Its interaction with signaling pathways such as Wnt/β-catenin and PI3K/AKT highlights its potential involvement in tumorigenesis.

The NR2C2AP antibody is a critical tool for detecting endogenous NR2C2AP expression and localization in tissues or cell lines via techniques like Western blot, immunohistochemistry, or immunofluorescence. It aids in elucidating the protein’s molecular functions, particularly its interplay with NR2C2 and other regulatory networks. Studies using this antibody contribute to understanding disease mechanisms, biomarker discovery, and therapeutic targeting. However, challenges remain in fully characterizing its biological roles due to the complexity of lncRNA-protein interactions. Validating antibody specificity through knockdown/knockout controls is essential to ensure reliable experimental outcomes.

       
關(guān)鍵字: NR2C2AP抗體;NR2C2AP;NR2C2AP Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學(xué)試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
普通會員
  • 公司成立:2年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
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