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ACOT11抗體,Rabbit Polyclonal ACOT11 Antibody
  • ACOT11抗體,Rabbit Polyclonal ACOT11 Antibody
  • ACOT11抗體,Rabbit Polyclonal ACOT11 Antibody
  • ACOT11抗體,Rabbit Polyclonal ACOT11 Antibody

ACOT11抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-13
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:ACOT11抗體英文名稱:Rabbit Polyclonal ACOT11 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3723 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: ACOT11
2025-05-13 ACOT11抗體 Rabbit Polyclonal ACOT11 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3723 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB咨詢技術 Human,Mouse,Rat
IF咨詢技術 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術咨詢 Human,Mouse,Rat
FCM咨詢技術 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesBFIT; THEA; THEM1; STARD14
WB Predicted band size68 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human ACOT11
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human liver cancer tissue, Human fetal kidney tissue, Primary antibody: P07750(ACOT11 Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 90 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P07750(ACOT11 Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07750(ACOT11 Antibody) at dilution 1/40. (Original magnification: ×200)    


           

參考文獻

以下是關于ACOT11抗體的3-4篇文獻示例(注:以下信息為模擬虛構,僅供參考):

1. **文獻名稱**: *ACOT11 regulates lipid metabolism and promotes hepatocellular carcinoma progression*

**作者**: Zhang Y, et al. (2020)

**摘要**: 本研究利用ACOT11特異性抗體,發(fā)現(xiàn)ACOT11在肝癌組織中顯著高表達,并通過調控脂肪酸氧化促進腫瘤生長,提示其作為肝癌治療潛在靶點。

2. **文獻名稱**: *Characterization of ACOT11 enzyme activity and antibody validation in metabolic syndrome models*

**作者**: Smith JL, et al. (2018)

**摘要**: 通過開發(fā)并驗證ACOT11多克隆抗體,證實ACOT11在肥胖小鼠肝臟中表達上調,其硫酯酶活性與胰島素抵抗相關。

3. **文獻名稱**: *ACOT11 deficiency alters cellular lipid composition and inflammatory responses*

**作者**: Brown KR, et al. (2021)

**摘要**: 使用ACOT11敲除小鼠模型及特異性抗體,證明ACOT11缺失導致巨噬細胞脂質累積異常,并增強促炎因子分泌。

4. **文獻名稱**: *Proteomic analysis of ACOT11 interaction network in adipocytes*

**作者**: Lee S, et al. (2019)

**摘要**: 通過免疫共沉淀(Co-IP)結合ACOT11抗體,揭示其在脂肪細胞中與PPARγ等代謝調控蛋白相互作用,影響脂滴形成。

(注:實際文獻需通過PubMed、Google Scholar等平臺檢索關鍵詞“ACOT11 antibody”或“acyl-CoA thioesterase 11”獲取。)

       

背景信息

The ACOT11 (Acyl-CoA Thioesterase 11) antibody is a tool used to study the function and expression of the ACOT11 enzyme, which belongs to the acyl-CoA thioesterase family. ACOT11 catalyzes the hydrolysis of acyl-CoA thioesters to free fatty acids and coenzyme A, regulating lipid metabolism and cellular energy homeostasis. It is implicated in diverse biological processes, including fatty acid oxidation, lipid signaling, and inflammation.

ACOT11 is localized in mitochondria and peroxisomes, with tissue-specific expression patterns, notably high in the liver, kidney, and brain. Research suggests its involvement in metabolic disorders, neurodegenerative diseases, and cancer. For instance, ACOT11 overexpression has been linked to altered lipid profiles in hepatocellular carcinoma, while its downregulation may influence neuroinflammation in Alzheimer’s disease.

The ACOT11 antibody enables detection and quantification of the protein via techniques like Western blotting, immunohistochemistry, and immunofluorescence. It aids in exploring ACOT11’s role in lipid metabolism pathways, its interaction with other enzymes (e.g., ACSL), and its potential as a therapeutic target. Recent studies also highlight its regulatory effects on PPARα signaling, linking it to adaptive responses during fasting or stress. Continued research with this antibody may uncover novel mechanisms in metabolic syndrome and cancer progression.

       
關鍵字: ACOT11抗體;ACOT11;ACOT11 Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學、質量管理體系。并不斷致力于技術創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內
主營行業(yè) 中間體,化學試劑 經(jīng)營模式 貿易,工廠,試劑,定制,服務
  • 湖北瑞和寧生物科技有限公司
普通會員
  • 公司成立:2年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

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