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ALDH3B1抗體,Rabbit Polyclonal ALDH3B1 Antibody
  • ALDH3B1抗體,Rabbit Polyclonal ALDH3B1 Antibody
  • ALDH3B1抗體,Rabbit Polyclonal ALDH3B1 Antibody
  • ALDH3B1抗體,Rabbit Polyclonal ALDH3B1 Antibody

ALDH3B1抗體

價(jià)格 詢(xún)價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-13
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱(chēng):ALDH3B1抗體英文名稱(chēng):Rabbit Polyclonal ALDH3B1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3771 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類(lèi)別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): ALDH3B1
2025-05-13 ALDH3B1抗體 Rabbit Polyclonal ALDH3B1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3771 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢(xún)技術(shù) Human,Mouse,Rat
IF咨詢(xún)技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢(xún) Human,Mouse,Rat
FCM咨詢(xún)技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesALDH4; ALDH7
WB Predicted band size52 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human ALDH3B1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human normal kidney tissue, Human liver tissue, human liver cancer tissue, Primary antibody: P07813(ALDH3B1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 45 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07813(ALDH3B1 Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07813(ALDH3B1 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于ALDH3B1抗體的3篇參考文獻(xiàn),按文獻(xiàn)名稱(chēng)、作者和摘要內(nèi)容概括列出:

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1. **"Aldehyde dehydrogenase 3B1 (ALDH3B1) promotes cellular resistance to oxidative stress in hepatocellular carcinoma"**

*Authors: Chen Y, et al.*

摘要:研究利用ALDH3B1特異性抗體,通過(guò)免疫組化分析發(fā)現(xiàn)ALDH3B1在肝癌組織中高表達(dá),其通過(guò)清除氧化應(yīng)激產(chǎn)物(如4-HNE)增強(qiáng)癌細(xì)胞存活能力,提示其作為肝癌治療潛在靶點(diǎn)。

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2. **"ALDH3B1 as a prognostic biomarker in non-small cell lung cancer: Immunohistochemical analysis using a novel monoclonal antibody"**

*Authors: Smith RJ, et al.*

摘要:開(kāi)發(fā)了一種新型ALDH3B1單克隆抗體,驗(yàn)證其在非小細(xì)胞肺癌(NSCLC)組織中的特異性。研究發(fā)現(xiàn)ALDH3B1高表達(dá)與患者不良預(yù)后相關(guān),可能通過(guò)調(diào)控腫瘤干細(xì)胞特性促進(jìn)轉(zhuǎn)移。

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3. **"Differential expression of ALDH3B1 isoforms in breast cancer and their interaction with chemotherapeutic agents"**

*Authors: Gupta S, et al.*

摘要:通過(guò)Western blot和免疫熒光(使用ALDH3B1抗體)發(fā)現(xiàn)乳腺癌細(xì)胞中ALDH3B1存在兩種亞型,其中一種亞型與化療耐藥性相關(guān),機(jī)制涉及代謝解毒途徑的激活。

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**備注**:以上文獻(xiàn)名為示例,實(shí)際研究中建議通過(guò)PubMed或Web of Science搜索具體文獻(xiàn)。若需全文,可使用DOI或聯(lián)系作者獲取。

       

背景信息

The aldehyde dehydrogenase 3 family member B1 (ALDH3B1) is an enzyme belonging to the ALDH superfamily, which plays a critical role in detoxifying endogenous and exogenous aldehydes by oxidizing them into carboxylic acids. ALDH3B1 is implicated in cellular defense against oxidative stress, metabolic regulation, and potential involvement in diseases such as cancer, neurodegenerative disorders, and alcohol-related pathologies. Its expression varies across tissues, with higher levels observed in the liver, kidneys, and respiratory tract.

ALDH3B1 antibodies are essential tools for detecting and quantifying ALDH3B1 protein expression in research applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). These antibodies aid in studying ALDH3B1's physiological roles, including its contribution to drug resistance in cancers, metabolic reprogramming, and response to oxidative damage. Commercially available ALDH3B1 antibodies are typically developed using immunogens derived from specific peptide sequences or recombinant proteins, ensuring specificity through validation in knockdown models or ALDH3B1-deficient cell lines.

Research utilizing ALDH3B1 antibodies has revealed its dual role as both a detoxifying enzyme and a potential biomarker. For instance, elevated ALDH3B1 levels are linked to poor prognosis in certain cancers, suggesting its utility in diagnostic or therapeutic strategies. However, functional studies remain limited, highlighting the need for further exploration of its mechanistic pathways. Reliable antibodies are thus critical for advancing understanding of ALDH3B1's multifunctional biology and its implications in disease pathogenesis.

       
關(guān)鍵字: ALDH3B1抗體;ALDH3B1;ALDH3B1 Antibody;

公司簡(jiǎn)介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國(guó)內(nèi)外廣大用戶(hù)的信任。
成立日期 2024-06-24 (3年) 注冊(cè)資本 50萬(wàn)(元)
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以?xún)?nèi)
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  • 湖北瑞和寧生物科技有限公司
普通會(huì)員
  • 公司成立:3年
  • 注冊(cè)資本:50萬(wàn)(元)
  • 企業(yè)類(lèi)型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
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