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NAT8抗體,Rabbit Polyclonal NAT8 Antibody
  • NAT8抗體,Rabbit Polyclonal NAT8 Antibody
  • NAT8抗體,Rabbit Polyclonal NAT8 Antibody
  • NAT8抗體,Rabbit Polyclonal NAT8 Antibody

NAT8抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-14
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:NAT8抗體英文名稱:Rabbit Polyclonal NAT8 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3844 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): NAT8
2025-05-14 NAT8抗體 Rabbit Polyclonal NAT8 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3844 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/1000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesGLA; CML1; Hcml1; ATase2; TSC501; TSC510
WB Predicted band size26 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human NAT8
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse kidney tissue, Mouse liver tissue, Primary antibody: P07945(NAT8 Antibody) at dilution 1/237.5, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P07945(NAT8 Antibody) at dilution 1/50. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P07945(NAT8 Antibody) at dilution 1/50. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于NAT8抗體的3篇參考文獻(xiàn)示例(注:文獻(xiàn)為虛構(gòu)示例,實(shí)際文獻(xiàn)需通過學(xué)術(shù)數(shù)據(jù)庫檢索確認(rèn)):

1. **文獻(xiàn)名稱**:*NAT8 Expression in Alzheimer's Disease Brain Tissue*

**作者**:Smith A, et al.

**摘要**:研究利用NAT8特異性抗體檢測阿爾茨海默病患者腦組織中NAT8蛋白的表達(dá)水平,發(fā)現(xiàn)其表達(dá)與淀粉樣斑塊沉積呈負(fù)相關(guān),提示NAT8可能參與神經(jīng)退行性調(diào)控。

2. **文獻(xiàn)名稱**:*NAT8B as a Novel Biomarker in Renal Cell Carcinoma*

**作者**:Chen L, et al.

**摘要**:通過開發(fā)高特異性NAT8抗體進(jìn)行免疫組化分析,揭示NAT8B在腎癌細(xì)胞中顯著高表達(dá),并與其侵襲性相關(guān),為癌癥診斷提供潛在靶點(diǎn)。

3. **文獻(xiàn)名稱**:*Functional Characterization of NAT8 in Cellular Acetylation Pathways*

**作者**:Yamamoto K, et al.

**摘要**:研究利用NAT8抗體進(jìn)行Western blot和免疫熒光實(shí)驗,證實(shí)NAT8通過調(diào)控小分子代謝物的乙酰化影響細(xì)胞氧化應(yīng)激反應(yīng),為代謝疾病研究提供新方向。

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**提示**:實(shí)際文獻(xiàn)建議通過 **PubMed** 或 **Google Scholar** 檢索關(guān)鍵詞“NAT8 antibody”、“NAT8 immunolocalization”等獲取。部分研究可能聚焦于NAT8的生物學(xué)功能而非抗體開發(fā),需結(jié)合具體需求篩選。

       

背景信息

NAT8 (N-acetyltransferase 8), also known as cysteine conjugate N-acetyltransferase, is an enzyme encoded by the NAT8 gene. It belongs to the N-acetyltransferase family and plays a role in metabolic processes, particularly in the acetylation of cysteine S-conjugates and xenobiotic compounds. NAT8 is primarily expressed in the kidney and liver, where it contributes to detoxification pathways and metabolic homeostasis. Dysregulation of NAT8 has been implicated in various pathologies, including renal diseases and cancers, where altered acetylation processes may influence cell proliferation or apoptosis.

NAT8 antibodies are immunological tools developed to detect and quantify NAT8 protein expression in research settings. These antibodies are critical for studying NAT8's biological functions, tissue-specific distribution, and its potential role in disease mechanisms. In cancer research, NAT8 antibodies have been used to investigate its overexpression in certain tumors, such as glioblastoma and renal cell carcinoma, suggesting its possible involvement in tumor metabolism or drug resistance. Additionally, NAT8 antibodies aid in exploring epigenetic regulation, as NAT8 interacts with histone modifiers, linking metabolic activity to chromatin remodeling.

Validated for applications like Western blotting, immunohistochemistry, and immunofluorescence, NAT8 antibodies help identify biomarkers for diagnostic or therapeutic targeting. Recent studies also highlight NAT8's association with neurodegenerative conditions, expanding its relevance beyond metabolic disorders. However, specificity and cross-reactivity challenges require careful validation of these antibodies in experimental models. Overall, NAT8 antibodies serve as vital reagents for unraveling the enzyme's multifaceted roles in health and disease.

       
關(guān)鍵字: NAT8抗體;NAT8;NAT8 Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (3年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學(xué)試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
普通會員
  • 公司成立:3年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
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