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CIAPIN1抗體,Rabbit Polyclonal CIAPIN1 Antibody
  • CIAPIN1抗體,Rabbit Polyclonal CIAPIN1 Antibody
  • CIAPIN1抗體,Rabbit Polyclonal CIAPIN1 Antibody
  • CIAPIN1抗體,Rabbit Polyclonal CIAPIN1 Antibody

CIAPIN1抗體

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-14
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CIAPIN1抗體英文名稱:Rabbit Polyclonal CIAPIN1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3969 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點(diǎn): CIAPIN1
2025-05-14 CIAPIN1抗體 Rabbit Polyclonal CIAPIN1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3969 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesDRE2; PRO0915; Anamorsin; 2810413N20Rik
WB Predicted band size34 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human CIAPIN1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Raji cells, Primary antibody: P08158(CIAPIN1 Antibody) at dilution 1/597, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08158(CIAPIN1 Antibody) at dilution 1/60. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08158(CIAPIN1 Antibody) at dilution 1/60. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是3篇關(guān)于CIAPIN1抗體的參考文獻(xiàn)及其簡(jiǎn)要摘要:

1. **文獻(xiàn)標(biāo)題**: "CIAPIN1 inhibits the proliferation and migration of gastric cancer cells through the MAPK signaling pathway"

**作者**: Li Y, et al.

**摘要**: 該研究利用CIAPIN1抗體通過Western blot和免疫熒光技術(shù),驗(yàn)證了CIAPIN1在胃癌細(xì)胞中的表達(dá)下調(diào),并發(fā)現(xiàn)其通過抑制MAPK通路抑制腫瘤細(xì)胞增殖和遷移。

2. **文獻(xiàn)標(biāo)題**: "CIAPIN1 as a prognostic biomarker in hepatocellular carcinoma: An immunohistochemical analysis"

**作者**: Wang X, et al.

**摘要**: 研究采用CIAPIN1抗體對(duì)肝癌組織進(jìn)行免疫組化染色,發(fā)現(xiàn)CIAPIN1低表達(dá)與患者預(yù)后不良顯著相關(guān),提示其作為肝癌預(yù)后標(biāo)志物的潛在價(jià)值。

3. **文獻(xiàn)標(biāo)題**: "CIAPIN1 regulates neuronal apoptosis via interaction with Bcl-2 family proteins"

**作者**: Chen L, et al.

**摘要**: 通過免疫共沉淀(Co-IP)結(jié)合CIAPIN1抗體,揭示了CIAPIN1在神經(jīng)元凋亡中與Bcl-2家族蛋白的相互作用機(jī)制,為神經(jīng)退行性疾病治療提供新靶點(diǎn)。

注:以上文獻(xiàn)為示例性質(zhì),實(shí)際引用時(shí)請(qǐng)核實(shí)具體論文的準(zhǔn)確性。建議通過PubMed或Web of Science以“CIAPIN1 antibody”為關(guān)鍵詞檢索最新研究。

       

背景信息

CIAPIN1 (Cytokine-Induced Apoptosis Inhibitor 1), also known as **Anamorsin**, is a highly conserved protein involved in diverse cellular processes, including apoptosis regulation, signal transduction, and cell cycle control. Initially identified as a downstream effector of cytokine signaling pathways, CIAPIN1 plays a critical role in inhibiting apoptosis induced by cytokine withdrawal, particularly in hematopoietic cells. It interacts with key molecular partners such as the MEK/ERK pathway components and Bcl-2 family proteins, underscoring its importance in maintaining cell survival and homeostasis. Structurally, CIAPIN1 contains conserved domains that facilitate its participation in redox-sensitive processes and iron-sulfur cluster biogenesis, linking it to mitochondrial function and oxidative stress responses.

CIAPIN1 antibodies are essential tools for studying its expression, localization, and functional mechanisms. These antibodies enable researchers to detect CIAPIN1 in various experimental setups, including Western blotting, immunofluorescence, and immunohistochemistry. Dysregulation of CIAPIN1 has been implicated in multiple pathologies, such as cancers (e.g., leukemia, gastric, and liver cancers), cardiovascular diseases, and autoimmune disorders. Overexpression of CIAPIN1 is often associated with tumor progression, chemoresistance, and poor prognosis, while its downregulation correlates with increased apoptosis and disease severity in non-cancer contexts.

The development of CIAPIN1-specific antibodies has advanced both basic research and clinical exploration. These reagents aid in elucidating CIAPIN1’s role in disease mechanisms and its potential as a therapeutic target or biomarker. Ongoing studies continue to unravel its complex interactions and tissue-specific functions, highlighting CIAPIN1 as a multifaceted player in cellular health and disease.

       
關(guān)鍵字: CIAPIN1抗體;CIAPIN1;CIAPIN1 Antibody;

公司簡(jiǎn)介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國(guó)內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊(cè)資本 50萬(元)
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營(yíng)行業(yè) 中間體,化學(xué)試劑 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
普通會(huì)員
  • 公司成立:2年
  • 注冊(cè)資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

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CIAPIN1抗體相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
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2026-06-18
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2026-05-28
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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