描述(Description)
IL-7 protein is an important hematopoietic cytokine that is essential for the development, expansion and survival of T cells and B cells, regulating mature lymphocyte populations and maintaining lymphatic homeostasis. IL-7 interacts with IL7RA and CSF2RG subunits, activates kinases, including JAK1 or JAK3, and initiates signaling cascades, such as the PI3K/Akt/mTOR or JAK-STAT5 pathway. IL-7 Protein, Human (HEK293, His) is the recombinant human-derived IL-7 protein, expressed by HEK293 , with C-6*His labeled tag.
純度(Purity)
≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining)
生物活性(Bioactivity)
Measured in a cell proliferation assay using NALM-6 human pre-B cells. The ED50 for this effect is ≤30ng/ml.
氨基酸序列(Target Protein Sequence)
DCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMG/VAILTKEH
制劑(Trait)
Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
復(fù)溶(Reconstitution)
It is recommended to redissolve in sterile deionized water.
保存條件&效期(Storage & Stability)
36 months at 2°C to 8°C in lyophilized state
6 months at -20°C to -80°C under sterile conditions after reconstitution
7-10 days at 2°C to 8°C under sterile conditions after reconstitution
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
運(yùn)輸方式(Shipping)
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
生物活性(Bioactivity) |
Measured in a cell proliferation assay using NALM-6 human pre-B cells. The ED50 for this effect is ≤30ng/ml |
電泳(SDS-PAGE) |
Recombinant Human IL-7 SDS-PAGE under reducing (R) & Non-reducing conditions. The gel was stained with Y02401 SDS-PAGE |
特別提示:本公司的所有產(chǎn)品僅用于工業(yè)應(yīng)用或者科學(xué)研究等非醫(yī)療目的,不可用于人類或動物的臨床診斷或者治療,非藥用,非食用。
關(guān)鍵字: GMP級;高純度;批間一致;生物活性;科研專供;
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