| 價(jià)格 | 詢(xún)價(jià) | ||
| 包裝 | 100ug | 500ug | 1000ug |
| 最小起訂量 | 100ug |
| 發(fā)貨地 | 北京 |
| 更新日期 | 2026-06-17 |
| 中文名稱(chēng):IL-2RB & IL-2RG蛋白 | 英文名稱(chēng):IL-2RB & IL-2RG |
| 品牌: 百普賽斯 | 產(chǎn)地: 北京 |
| 保存條件: -20°C to -70°C | 純度規(guī)格: 99.9% |
| 產(chǎn)品類(lèi)別: 重組蛋白 | |
| 貨號(hào): IL-2RB & IL-2RG | 用途范圍: 科研 |
| 規(guī)格: 100ug | 是否進(jìn)口: 否 |
分子別名(Synonym)
IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG
表達(dá)區(qū)間及表達(dá)系統(tǒng)(Source)
Human IL-2RB&IL-2RG Heterodimer Protein, His Tag&Twin-Strep Tag (ILG-H5283) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Asp 239 (IL-2RB) & Leu 23 - Asn 254 (IL-2RG) (Accession # P14784-1 (IL-2RB) & P31785-1 (IL-2RG)).
Predicted N-terminus: Ala 27 (IL-2RB) & Leu 23 (IL-2RG)
蛋白結(jié)構(gòu)(Molecular Characterization)

Human IL-2RB&IL-2RG Heterodimer Protein, His Tag&Twin-Strep Tag is produced by co-expression of IL-2RB and IL-2RG, has a calculated MW of 29.9 kDa (IL-2RB) and 34.1 kDa (IL-2RG). Subunit IL-2RB is fused with a polyhistidine tag at the C-terminus and subunit IL-2RG is fused with Twin-Strep tag at the C-terminus. The protein migrates as 40-44 kDa and 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method / rFC method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.


背景介紹
白細(xì)胞介素-2受體β亞基與γ亞基共同構(gòu)成IL-2的受體復(fù)合物。其中γ亞基是多種白細(xì)胞介素受體的共有組分(γc鏈),可在白細(xì)胞素刺激下與銜接蛋白SHB發(fā)生相互作用。該亞基可能與IL15RA協(xié)同參與IL15介導(dǎo)的中性粒細(xì)胞吞噬激活過(guò)程。β亞基則負(fù)責(zé)介導(dǎo)受體依賴(lài)性?xún)?nèi)吞作用,并轉(zhuǎn)導(dǎo)IL-2的促有絲分裂信號(hào)。IL-2受體存在三種構(gòu)象態(tài):高親和力二聚體、中親和力單體(β亞基)及低親和力單體(α亞基),其中高/中親和力構(gòu)象均需結(jié)合γ亞基方可形成完整功能單元。
| 成立日期 | 2010-07-22 (16年) | 注冊(cè)資本 | 8000萬(wàn)人民幣 |
| 員工人數(shù) | 500人以上 | 年?duì)I業(yè)額 | ¥ 1億以上 |
| 主營(yíng)行業(yè) | 醫(yī)藥中間體,原料藥,激素類(lèi),氨基糖苷類(lèi),中樞神經(jīng)系統(tǒng)用藥 | 經(jīng)營(yíng)模式 | 工廠(chǎng),試劑 |
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