Product Name：LXY3
CAS No.：1095009-44-1
Synonyms：阻斷肽LXY2
Catalog No.：220P080
Brand：Typeptide Biotech（肽研生物）
Description：LXY3是一種 VLA-3 阻斷肽，是由8個氨基酸組成的環(huán)狀多肽，通過抑制中性粒細胞表面的整合素 α3β1 (VLA-3) 與基底膜中層粘連蛋白的相互作用，阻止中性粒細胞穿過腫瘤血管基底膜屏障的遷移。LXY3 被用于阻斷中性粒細胞介導的納米顆粒從血管周圍池釋放到腫瘤間質(zhì)的過程。LXY3 常用于乳腺癌的靶向成像。
LXY3 is a VLA-3 blocking peptide composed of eight amino acids in a cyclic structure. It inhibits the interaction between integrin α3β1 (VLA-3) on the surface of neutrophils and laminin in the basement membrane, thereby preventing the migration of neutrophils across the tumor vascular basement membrane barrier. LXY3 is used to block the release of neutrophil-mediated nanoparticles from the perivascular pool into the tumor interstitium. LXY3 is commonly used for targeted imaging of breast cancer.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | {d-Cys}-{d-Asp}-G-{Tyr(3-NO2)}-G-{Hyp}-N-{d-Cys}-NH2 (disulfide bridge: d-Cys1-d-Cys8) |
Sequence(3-letter code) | {d-Cys}-{d-Asp}-Gly-{Tyr(3-NO2)}-Gly-{Hyp}-Asn-{d-Cys}-NH2 (disulfide bridge: d-Cys1-d-Cys8) |
Peptide Structure | 
|
Molecular Formula | C32H43N11O15S2 |
Molecular Weight | 885.88 |
訂購聯(lián)系方式：
南京肽研生物生物科技有限公司
手機號：19961912513(微信同號)
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關(guān)鍵字： LXY3;阻斷肽LXY2;1095009-44-1;多肽;多肽合成;
肽研生物坐落于國家級新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠信、嚴 謹、務(wù)實”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。