產(chǎn)品概述
TATA Box Binding Protein (9D1) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB
Human,Rat,Mouse
產(chǎn)品性能
Unconjugated
Unmodified
IgG1
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
TBP
TBP; GTF2D1; TF2D; TFIID; TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit
6908
P20226
產(chǎn)品應(yīng)用
WB: 1:500-1:1000
Calculated MW: 38 kDa; Observed MW: 35-45 kDa
研究背景
As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This protein is not suitable for samples where the nuclear envelope has been removed.
研究領(lǐng)域
Epigenetics and Nuclear Signaling
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