產(chǎn)品概述
LIN28A (2C1) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB
Human,Mouse
產(chǎn)品性能
Unconjugated
Unmodified
IgG2a
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
LIN28A
CSDD1; FLJ12457; LIN 28; Lin-28A; LIN28; LIN28A; LN28A_HUMAN; Protein lin-28 homolog A; ZCCHC1; Zinc finger CCHC domain-containing protein 1.
79727
Q9H9Z2
產(chǎn)品應用
WB: 1:500-1:1000
Calculated MW: 23 kDa; Observed MW: 26 kDa
研究背景
Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.
研究領域
Epigenetics and Nuclear Signaling
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