產(chǎn)品概述
SOD2 (4C4) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB
Human
產(chǎn)品性能
Unconjugated
Unmodified
IgG2b
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
SOD2
IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2
6648
P04179
產(chǎn)品應(yīng)用
WB: 1:500-1:1000
Calculated MW: 25 kDa; Observed MW: 22 kDa
研究背景
SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle.
研究領(lǐng)域
Cell Biology
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