產(chǎn)品概述
PYK2 (4B4) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB,IHC-P
Human
產(chǎn)品性能
Unconjugated
Unmodified
IgG2a
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Ascitic Fluid
免疫原
PTK2B
PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
2185
Q14289
產(chǎn)品應(yīng)用
WB: 1:500-1:1000 IHC: 1:50-1:100
Calculated MW: 116 kDa; Observed MW: 116 kDa
研究背景
PYK2 a nonreceptor tyrosine kinase of the Fak family. Predominantly expressed in the cells derived from hematopoietic lineages and in the central nervous system. PYK2 is one of the signaling mediators for G-protein-coupled receptors. Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. Interacts with the SH2 domain of Grb2.
研究領(lǐng)域
Signal Transduction
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