產(chǎn)品概述
p53 (2D10) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB,IHC-F,IHC-P,ICC/IF
Human
產(chǎn)品性能
Unconjugated
Unmodified
IgG1
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
TP53
TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
7157
P04637
產(chǎn)品應用
WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200
Calculated MW: 44 kDa; Observed MW: 53 kDa
研究背景
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.
研究領域
Cell Biology
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